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Biomaterials for Cancer Therapeutics: Evolution and Innovation, Second Edition, discusses the role and potential of biomaterials in treating this prevalent disease. The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Part Two discusses synthetic vaccines, proteins and polymers for cancer therapeutics. Part Three focuses on theranosis and drug delivery systems, while the final set of chapters look at biomaterial therapies and cancer cell interaction.
Cancer affects people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is being developed to target, treat and prevent cancer. Hence, this book is a welcomed resource to the discussion.
Sommario
1. Cancer: so common and so difficult to deal with
2. Phenotypic evolution of cancer cells: structural requirements for survival
3. Immunoactive drug carriers in cancer therapy
4. Treating cancer by delivering drug nanocrystals
5. Polymer therapeutics
6. pH-sensitive biomaterials for cancer therapy and diagnosis
7. Nucleic acid anticancer agents
8. Biomaterials for gene editing therapeutics
9. Liquid biopsies for early cancer detection
10. Nanotechnology for cancer screening and diagnosis: from innovations to clinical applications
11. Advances and clinical challenges in biomaterials for in vivo tumor imaging
12. Macroscopic fluorescence lifetime-based Fo ¨rster resonance energy transfer imaging for quantitative ligandreceptor binding
13. Suppression of cancer stem cells
14. Comparison of two- and three-dimensional cancer models for assessing potential cancer therapeutics
15. Engineered tumor models for cancer biology and treatment
16. Cancer mechanobiology: interaction of biomaterials with cancer cells
17. Immunostimulatory materials
18. Biomaterials for cancer immunotherapy
19. Lymph node targeting for improved potency of cancer vaccine
20. Immunogenic clearance-mediated cancer vaccination
21. The future of drug delivery in cancer treatment
22. Development of clinically effective formulations for anticancer applications: why it is so difficult?
Info autore
Kinam Park is Showalter Distinguished Professor of Biomedical Engineering & Professor of Pharmaceutics at Purdue University, USA. His research focuses in the areas of nano/micro particles, polymer micelles, drug-eluting stents, extracellular matrix, fast dissolving tablets, and smart hydrogels.
