Mathematica for Bioinformatics - A Wolfram Language Approach to Omics

This book offers a comprehensive introduction to using Mathematica and the Wolfram Language for Bioinformatics. The chapters build gradually from basic concepts and the introduction of the Wolfram Language and coding paradigms in Mathematica, to detailed worked examples derived from typical research applications using Wolfram Language code. The coding examples range from basic sequence analysis, accessing genomic databases, differential gene expression, and machine learning implementations to time series analysis of longitudinal omics experiments, multi-omics integration and building dynamic interactive bioinformatics tools using the Wolfram Language. The topics address the daily bioinformatics needs of a broad audience: experimental users looking to understand and visualize their data, beginner bioinformaticians acquiring coding expertise in providing biological research solutions, and practicing expert bioinformaticians working on omics who wish to expand their toolset to includethe Wolfram Language.

Sommario

1 Introduction to Bioinformatics.- 2. A Mathematica Primer for Bioinformaticians.- 3. Statistics for Genomic Analysis.- 4. Genomic Sequences.- 5. Databases.- 6. Transcriptomics.- 7. Proteomics.- 8. Metabolomics.- 9. Systems Biology.- 10. Networks.- 11. Time Series Analysis.- 12. Omics Integration and Systems Medicine.- 13. Bioinformatics Development with Mathematica.

Riassunto

Illustrates research applications with detailed, worked out examples
Provides complete code companion executable in Mathematica notebooks
Contains complete instructions for users write their own application in the wolfram language  

Dettagli sul prodotto

• Autori: George Mias
• Editore: Springer, Berlin
• Lingue: Inglese
• Formato: Tascabile
• Pubblicazione: 01.01.2018
• EAN: 9783030101923
• ISBN: 978-3-0-3010192-3
• Pagine: 384
• Dimensioni: 155 mm x 21 mm x 235 mm
• Peso: 611 g
• Illustrazioni: XVI, 384 p. 175 illus., 156 illus. in color.
• Categorie: Scienze naturali, medicina, informatica, tecnica > Biologia > Altro; B, METABOLISM, bioinformatics, Life sciences: general issues, Biomedical and Life Sciences, Medical Genetics, Cellular biology (cytology), Systems Biology, Information technology: general issues, Biostatistics, Computational and Systems Biology, Computational Biology/Bioinformatics, Metabolomics, Computational biology, Computer Appl. in Life Sciences, Microarrays