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Currently an estimated 17 million nuclear medicine procedures are performed each year in the US and constantly evolving, as new radiopharmaceuticals and imaging techniques are introduced for better diagnosis and treatment of human diseases. In keeping up with new developments, the Seventh Edition of Fundamentals of Nuclear Pharmacy chronicles the advancements in radiopharmaceuticals and their use in clinical applications. It discusses basic concepts such as the atom, radioactive decay, instrumentation and production of radionuclides, and explores the design, labeling, characteristics and quality control of radiopharmaceuticals. Radiation regulations and diagnostic and therapeutic applications of radiopharmaceuticals are detailed.
Thoroughly updated, the Seventh Edition includes new topics such as alternative productions of 99Mo; production of 64Cu, 86Y, 89Zr, 177Lu, 223Ra; synthesis and clinical uses of new radiopharmaceuticals such as DaTscan, Xofigo, Amyvid, Neuraceq, Vizamyl, Axumin and 68Ga-DOTATATE; dosimetry of new radiopharmaceuticals; theranostic agents and translational medicine. It features numerous examples, diagrams, and images to further clarify the information and offers end- of-chapter questions to help readers assess their comprehension of the material. Recognized as a classic text on nuclear chemistry and pharmacy and acclaimed for its concise and easy-to-understand presentation, Fundamentals of Nuclear Pharmacy is an authoritative resource for nuclear medicine physicians, residents, students, and technologists.
Sommario
The Atom.- Radioactive Decay.- Instruments for Radiation Detection and Measurement.- Production of Radionuclides.- Radionuclide Generators.- Radiopharmaceuticals and Methods of Radiolabeling.- Characteristics of Specific Radiopharmaceuticals.- Quality Control of Radiopharmaceuticals.- Nuclear Pharmacy.- Internal Radiation Dosimetry.- Radiation Regulations, Protection, and Uses.- In Vitro and In Vivo Nonimaging Tests.- Diagnostic Uses of Radiopharmaceuticals in Nuclear Medicine.- Molecular Imaging.- Therapeutic Uses of Radiopharmaceuticals in Nuclear Medicine.- Adverse Reactions to and Altered Biodistribution of Radiopharmaceuticals.
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Gopal B. Saha, PhD
Emeritus Staff
Cleveland Clinic
Cleveland, OH, USA
Gopal Saha, PhD, joined the Department of Nuclear Medicine at the Cleveland Clinic as Director of Nuclear Chemistry and Pharmacy in 1984. He established a nuclear pharmacy laboratory with full amenities for routine clinical studies and sponsored clinical trials, which has been highly acclaimed by Nuclear Regulatory Commission and Joint Commission Accreditation of Healthcare Organizations. He is the recipient of the Lifetime Achievement (Basic Science) Award of the Indo-American Society of Nuclear Medicine and of the Lifetime Achievement (Basic Science) Award of the Indo-American Society of Nuclear Medicine.
Riassunto
Presents the most recent advancements in radiopharmaceuticals and their use in nuclear medicine Discusses basic concepts such as the atom, radioactive decay, instrumentation, and production of radionuclides
Explores the design and labeling of radiopharmaceuticals and the characteristics and quality control of these compounds
