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The "omics" era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective. Written by leading experts in molecular biology, this text looks into the origins and evolution of the protein synthetic machinery.
Sommario
A review on the origin of the different codes for translation.- Evolution of ribosomes.- Origins and early evolution of ribosomes.- Evolution of ribosomes and ribosomal proteins.- Evolution of Class II aminoacyl synthetases from the antisense of the genes for Class I.- The translation process during the evolutionary transition from prokaryotes to eukaryotes.- Evolution of translational control: from archaea to eukarya.- Distribution of elongation family GTPases EF1A and EFL in basal alveolate lineages.- Evolution of mRNA structure; the eukaryotic mRNA 5´- and 3´- untranslated regions and their role in translational regulation.- How lower eukaryotes contribute on our understanding of eIF4E-dependent translation.- Evolution of functionally divergent eIF4Es and their roles in the regulation of mRNA recruitment and developmental processes.- Evolution of eIF4E and eIF4G interactions in trypanosomes.- Evolution of the functionally divergent eIF4E family members in deuterostomes.- Evolution of the eIF2alpha kinases and translational control.- Evolution and use of eIF2alpha kinases in the apicomplexans and their role in life history of the parasites Plasmodium falciparum and Toxoplasma gondii.- Evolution of the TOR pathway and translational regulation.- Origin and diversification of eIF4E-binding proteins.- Evolution of the protein synthesis machinery in mitochondria.- Relationship between plant translation initiation factors and RNA viruses: An evolutionary perspective.- Evolution of miRNAs and RNA binding proteins in eukaryotes.- Evolution of silencing foci across eukaryotes.- Evolutionary conservation of the machineries coupling RNA transport with translation in eukaryotes.
Info autore
Greco Hernández, PhD.Division of Basic ResearchNational Institute for Cancer (INCan)22 San Fernando Ave.Tlalpan. 14080 Mexico City, MexicoPhone: +52/55/56 28 04 33Fax: +52/55/51 71 05 30Email: greco.hernandez@gmail.com
Rosemary JagusInstitute of Marine and Environmental TechnologyUniversity of Maryland Center for Environmental Science701 E. Pratt StreetBaltimore MD 21202, U.S.Email: jagus@umces.edu
Riassunto
The “omics” era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective. Written by leading experts in molecular biology, this text looks into the origins and evolution of the protein synthetic machinery.
