Molecular & Cellular Targets for Anti-Epileptic Drugs

A new phase of anti-epileptic drugs (AEDs) investigation has begun in which new drugs can be designed to target specific epileptogenic mechanisms. A rational approach to therapy today requires not only a full awareness of phamacokinetics of AEDs but also a thorough knowledge of their molecular targets and of their influence on excitatory and inhibitory mechanisms in the brain. This book provides a multi-author systematic look at this subject, from neurobiological bases to clinical applications. It includes four sections dealing with fundamental aspects of cortical excitability, models of epileptic disorders, targets for anti-epileptic drugs and rational approaches to therapy. Each chapter provides a review of a specific topic prepared by well known scientists active in the field, introducing their most recent results in a concise and comprehensive form.

Dettagli sul prodotto

• Con la collaborazione di: G Avanzini (Editore), G. Avanzini (Editore), M. Avoli (Editore), G Regesta (Editore), M Avoli (Editore), P Tanganelli (Editore), G. Regesta (Editore), P. Tanganelli (Editore)
• Editore: John Libbey & Co
• Lingue: Inglese
• Formato: Tascabile
• Pubblicazione: 01.01.1997
• EAN: 9780861965540
• ISBN: 978-0-86196-554-0
• Pagine: 266
• Dimensioni: 180 mm x 249 mm x 20 mm
• Peso: 688 g
• Illustrazioni: Illustrations
• Serie: Current Problems in Epilepsy; Current problems in epilepsy
• Categoria: Scienze naturali, medicina, informatica, tecnica > Medicina > Branche cliniche