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Excerpt from The Medico-Chirurgical Review, and Journal of Practical Medicine, Vol. 21: 1st of April to 30th of September, 1834
After in¿ammation of the synovial membrane has subsided, the ¿uid is absorbed, and, in some instances, the joint regains its natural figure and mobility but, in other cases, stiffness and swelling remain. Sometimes the swelling retains the form it assumed whilst ¿uid was contained within the joint; this probably depends on the inner surface of the synovial membrane being lined with a thick layer of coagulable lymph. At other times, the swelling has nearly the natural form of the joint, when, perhaps, the sync vial membrane is thickened. In whatever way enlargement may be perpet uated, the patient is very liable to a recurrence of the in¿ammation from exposure to cold, unusual exercise, or indeed, without any evident reason. When the synovial membrane continues thickened, it occasionally happens, that not only a certain degree of in¿ammation still continues to linger in the part, but that the morbid action invades the other tissues, and terminates in ulceration of the cartilages and suppuration in the joint. In such a case, the history must form the foundation of our diagnosis, and amputation is generally the only remedy.
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