Fr. 207.00

Melanoma Development - Molecular Biology, Genetics and Clinical Application

Inglese · Copertina rigida

Spedizione di solito entro 6 a 7 settimane

Descrizione

Ulteriori informazioni


This book focuses on malignant melanoma, discussing the current state of scientific knowledge and providing insights into the underlying basic mechanisms, the molecular changes, genetics and genomics.
Human Melanoma is a dangerous type of skin cancer affecting an increasing population, and a better understanding of its development will help in finding sophisticated targeted therapies.
The second revised edition features the latest research findings and offers updates on the latest advances and potential novel melanoma therapies. 

It is a valuable resource for researchers and clinicians working in the fields of melanoma, cancer research and therapy as well as dermatology.

Sommario

Clinicopathologic Overview of Melanoma.- Revisiting Epidermal Melanocytes: Regulation of Their Survival, Proliferation, and Function in Human Skin.- Melanoma Epidemiology.- Melanoma Genetics and Genomics.- Transcriptional Regulation in Melanoma.- MiRNAs in Malignant Melanoma.- Altered Signal Transduction Pathways in Melanoma.- Proteases in Melanoma.- Cell-cell contacts in melanoma and the tumor microenvironment.- Regulation of Apoptosis in Melanoma Cells: Critical Targets for Therapeutic Strategies.- Senescence.-  Melanoma Stem Cells.- The Birth of Malignancy: Embryogenesis and Melanoma.- Tumor Microenvironment for Melanoma Cells.- Melanoma Model Systems.- New Approaches to Signaling.- Immune checkpoint inhibitors in melanoma define a new area in immunotherapy aiming for cure.

 

Info autore

Prof. Dr. Anja-Katrin Bosserhoff
Institute for Biochemistry
Friedrich-Alexander University Erlangen-NürnbergGermany 

Riassunto


This book focuses on malignant melanoma, discussing the current state of scientific knowledge and providing insights into the underlying basic mechanisms, the molecular changes, genetics and genomics.
Human Melanoma is a dangerous type of skin cancer affecting an increasing population, and a better understanding of its development will help in finding sophisticated targeted therapies.
The second revised edition features the latest research findings and offers updates on the latest advances and potential novel melanoma therapies. 

It is a valuable resource for researchers and clinicians working in the fields of melanoma, cancer research and therapy as well as dermatology.

Dettagli sul prodotto

Con la collaborazione di Anja K. Bosserhoff (Editore), Anj K Bosserhoff (Editore), Anja K Bosserhoff (Editore)
Editore Springer, Berlin
 
Lingue Inglese
Formato Copertina rigida
Pubblicazione 01.01.2017
 
EAN 9783319413174
ISBN 978-3-31-941317-4
Pagine 447
Dimensioni 159 mm x 23 mm x 239 mm
Peso 872 g
Illustrazioni VIII, 447 p. 36 illus., 26 illus. in color.
Serie Springer
Categorie Scienze naturali, medicina, informatica, tecnica > Medicina > Branche non cliniche

B, Biomedical and Life Sciences, Cancer Research, Biomedical Research, Cancer Biology, Targeted therapies, Tumor microenvironment

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