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In this book, leading international experts showcase the latest advances in research into Dupuytren disease and its clinical management. The coverage spans all relevant specialties, including cell biology, biomechanics, genomics, surgery, pharmacotherapy, and radiotherapy. The opening sections address epidemiology, cellular and extracellular events, and genetics. Treatment by means of collagenase injection, percutaneous needle fasciotomy, and other surgical and minimally invasive approaches is then extensively discussed. Comparative studies of different approaches are reviewed, and aspects of patient assessment, examined. The prevention and treatment of disease recurrences are also addressed. Further sections consider related conditions, other treatment options, and future pathways for research. This book should be read by all who treat or conduct research into Dupuytren disease. It is based on presentations delivered at the 2015 International Conference on Dupuytren Disease, held in Groningen, the Netherlands, which was designed to promote a coordinated global response to the disease involving patients, scientists, and clinicians.
Sommario
Epidemiology and Patients Views.- Cellular and Extra-cellular Events.- Genetics and Associations.- Collagenase Injection.- Percutaneous Needle Fasciotomy (PNF).- Assessment.- Comparative Studies.- Surgical Techniques and Recurrence.- Related Diseases and Other Treatments.- Future Paths of Research.
Info autore
Paul Werker is Professor and Chair of the Department of Plastic Surgery of the University Medical Center Groningen, the Netherlands. He is a diplomate of European Board of Plastic Reconstructive and Aesthetic Surgery (EBOPRAS) and the Federation of European Societies for Surgery of the Hand (FESSH). He is lead or co-author of 86 peer-reviewed PubMed-listed papers and co-editor of the book Dupuytren's Disease and Related Hyperproliferative Disorders. He won the Esser Prize for his work on the foreskin free flap in 2000.
Joseph Dias is Professor in Hand and Orthopaedic Surgery and Head of the Academic Department of Musculoskeletal Surgery at the University Hospitals of Leicester, UK. He is also a consultant hand and orthopaedic surgeon for the University Hospitals of Leicester. He is a Fellow of the Royal College of Surgeons in Edinburgh. His special interests include epidemiology of hand and wrist disorders and Dupuytren’s contracture. He has published over 150 scientific articles and has authored multiple national reports and NICE-accredited clinical pathways.
Charles Eaton is a hand surgeon in West Palm Beach, Florida, USA. He is the founder and Executive Director of the Dupuytren Foundation, a US nonprofit organization. Dr. Eaton has worked in academic and private practice and developed a Dupuytren-centered practice, which he closed in 2012 to volunteer full time for the Dupuytren Foundation. He has authored articles and book chapters on a range of hand surgery topics, with an emphasis on Dupuytren disease. He currently serves on the advisory board of the International Dupuytren Society and the Canadian Dupuytren Society.
Bert Reichert is a Professor of Plastic Surgery at Paracelsus Medical University, Nürnberg, Germany. He practices at the Clinic for Plastic, Reconstructive, and Hand Surgery, Center for Severe Burn Injuries, Paracelsus Medical University and at Klinikum Nürnberg-Süd, Nürnberg. He is an accredited specialist in General Surgery, Plastic Surgery, and Hand Surgery. His previous positions include Director of Plastic Surgery at Stadtlohn Hospital; Deputy Director, Department of Plastic Surgery, Burn Unit, University of Lübeck; and Associate Professor of Plastic Surgery, University of Regensburg.
Wolfgang Wach received his PhD in Solid State Physics from the University of Munich, Germany. After six years of research in ion implantation he worked in electronic design at Siemens and as General Manager at AT&T Microelectronics Europe. He started his own software company, CAL, in 1995 and the International Dupuytren Society (IDS) in 2003. IDS is a non-profit organization involving patients and physicians from all over the world who cooperate in providing information on Dupuytren disease, supporting patients, and finding a cure for the disease. Dr. Wach is currently one of the chairmen of IDS.
Riassunto
In this book, leading international experts showcase the latest advances in research into Dupuytren disease and its clinical management. The coverage spans all relevant specialties, including cell biology, biomechanics, genomics, surgery, pharmacotherapy, and radiotherapy. The opening sections address epidemiology, cellular and extracellular events, and genetics. Treatment by means of collagenase injection, percutaneous needle fasciotomy, and other surgical and minimally invasive approaches is then extensively discussed. Comparative studies of different approaches are reviewed, and aspects of patient assessment, examined. The prevention and treatment of disease recurrences are also addressed. Further sections consider related conditions, other treatment options, and future pathways for research. This book should be read by all who treat or conduct research into Dupuytren disease. It is based on presentations delivered at the 2015 International Conference on Dupuytren Disease, held in Groningen, the Netherlands, which was designed to promote a coordinated global response to the disease involving patients, scientists, and clinicians.
