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This book provides an up-to-date review of the use of thrombolytic therapy in the treatment of acute pulmonary embolism. It discusses the mechanisms of thrombosis; pharmacokinetics and pharmacodynamics of the most commonly used fibrinolytics; evidence-based results from multicenter control trials in which thrombolytic treatment was administered; criteria by which pulmonary embolism patients requiring thrombolysis are identified; and the use of thrombolytic therapy in special situations such as in in-transit thrombus and pregnancy. Focusing on peripheral intravenous thrombolysis, which can performed safely and effectively in emergency departments, hospital wards, and intensive critical care units in tertiary and community hospitals, Thrombolysis in Pulmonary Embolism is a valuable resource for cardiologists, pulmonologists, and internists.
Sommario
Venous Thrombosis.- Pharmokinetics and Pharmacodynamics of Fibrinolytics.- Thrombolytic Therapy: Evidence-Based Results from Multicenter Trials.- Current Guidelines and Recommendations for Thrombolysis Use.- Identifying Patients for Thrombolysis.- Bleeding Complications.- Thrombolysis in Special Situations.
Info autore
Carlos Jerjes-Sánchez, MD Instituto de Cardiología y Medicina Vascular TEC Salud del Sistema Tecnológico de Monterrey San Patricio 112 Real San Agustín 66278 San Pedro Garza García Nuevo León Mexico Dr. Jerjes-Sánchez is the recipient of several awards of the Mexican Society of Cardiology. He was designated Honorary Master of Hospital de Cardiologia, National Medical Center in 2011.
Riassunto
This book provides an up-to-date review of the use of thrombolytic therapy in the treatment of acute pulmonary embolism. It discusses the mechanisms of thrombosis; pharmacokinetics and pharmacodynamics of the most commonly used fibrinolytics; evidence-based results from multicenter control trials in which thrombolytic treatment was administered; criteria by which pulmonary embolism patients requiring thrombolysis are identified; and the use of thrombolytic therapy in special situations such as in in-transit thrombus and pregnancy. Focusing on peripheral intravenous thrombolysis, which can performed safely and effectively in emergency departments, hospital wards, and intensive critical care units in tertiary and community hospitals, Thrombolysis in Pulmonary Embolism is a valuable resource for cardiologists, pulmonologists, and internists.
