Fr. 189.00

Membrane Hydration - The Role of Water in the Structure and Function of Biological Membranes

Inglese · Copertina rigida

Spedizione di solito entro 6 a 7 settimane

Descrizione

Ulteriori informazioni

This book is about the importance of water in determining the structure, stability and responsive behavior of biological membranes. Water confers to lipid membranes unique features in terms of surface and mechanical properties. The analysis of the hydration forces, plasticiser effects, controlled hydration, formation of microdomains of confined water suggests that water is an active constituent in a water-lipid system.
The chapters describe water organization at the lipid membrane-water interphase, the water penetration, the long range water structure in the presence of lipid membranes by means of X-ray and neutron scattering, general polarization, fluorescent probes, ATR-FTIR and near infrared spectroscopies, piezo electric methods, computer simulation and surface thermodynamics.
Permeation, percolation, osmotic stress, polarization, protrusion, sorption, hydrophobicity, density fluctuations are treated in detail in self-assembled bilayers. Studies in lipid monolayers show the correlation of surface pressure with water activity and its role in peptide and enzyme interactions. The book concludes with a discussion on anhydrobiosis and the effect of water replacement in microdomains and its consequence for cell function.
New definitions of lipid/water interphases consider water not only as a structural-making solvent but as a mediator in signalling metabolic activity, modulating protein insertion and enzymatic activity, triggering oscillatory reactions and functioning of membrane bound receptors. Since these effects occur at the molecular level, membrane hydration appears fundamental to understand the behavior of nano systems and confined environments mimicking biological systems.
These insights in structural, thermodynamical and mechanical water properties give a base for new paradigms in membrane structure and function for those interested in biophysics, physical chemistry, biology, bio and nano medicine, biochemistry,
biotechnology and nano sciences searching for biotechnological inputs in human health, food industry, plant growing and energy conversion.

Sommario

Membrane Hydration: A hint to a new model for bio membranes.- Use of X-ray and neutron scattering methods with volume measurements to determine lipid bilayer structure and number of water molecules/lipid.- Water and Lipid Bilayers.- Hydration forces between lipid bilayers - a theoretical overview and a look on methods exploring dehydration.- Monitoring membrane hydration with 2-(dimethylamino)-6-acylnaphtalenes fluorescent probes.- Long-Range Lipid-Water Interaction as Observed by ATR-FTIR Spectroscopy.- Hydration And Nano confined Water. Some Insights From Computer Simulations.- Aquaphotomics: near infrared spectroscopy and water states in biological systems.- Hydration in lipid monolayers: Correlation of water activity and surface pressure.- Water at Biological Phase Boundaries: Its Role in Interfacial activation of enzymes and metabolic pathways.- Anhydrobiosis: An Unsolved Problem With Applications in Human Welfare.

Riassunto

This book is about the importance of water in determining the structure, stability and responsive behavior of biological membranes. Water confers to lipid membranes unique features in terms of surface and mechanical properties. The analysis of the hydration forces, plasticiser effects, controlled hydration, formation of microdomains of confined water suggests that water is an active constituent in a water-lipid system.The chapters describe water organization at the lipid membrane–water interphase, the water penetration, the long range water structure in the presence of lipid membranes by means of X-ray and neutron scattering, general polarization, fluorescent probes, ATR-FTIR and near infrared spectroscopies, piezo electric methods, computer simulation and surface thermodynamics.Permeation, percolation, osmotic stress, polarization, protrusion, sorption, hydrophobicity, density fluctuations are treated in detail in self-assembled bilayers. Studies in lipid monolayers show the correlation of surface pressure with water activity and its role in peptide and enzyme interactions. The book concludes with a discussion on anhydrobiosis and the effect of water replacement in microdomains and its consequence for cell function. New definitions of lipid/water interphases consider water not only as a structural-making solvent but as a mediator in signalling metabolic activity, modulating protein insertion and enzymatic activity, triggering oscillatory reactions and functioning of membrane bound receptors. Since these effects occur at the molecular level, membrane hydration appears fundamental to understand the behavior of nano systems and confined environments mimicking biological systems.These insights in structural, thermodynamical and mechanical water properties give a base for new paradigms in membrane structure and function for those interested in biophysics, physical chemistry, biology, bio and nano medicine, biochemistry,biotechnology and nano sciences searching for biotechnological inputs in human health, food industry, plant growing and energy conversion.

Dettagli sul prodotto

Con la collaborazione di Anibal Disalvo (Editore), E Anibal Disalvo (Editore), E. Anibal Disalvo (Editore)
Editore Springer, Berlin
 
Lingue Inglese
Formato Copertina rigida
Pubblicazione 01.01.2015
 
EAN 9783319190594
ISBN 978-3-31-919059-4
Pagine 284
Dimensioni 161 mm x 15 mm x 242 mm
Peso 622 g
Illustrazioni XVIII, 284 p.
Serie Subcellular Biochemistry
Subcellular Biochemistry
Categorie Scienze naturali, medicina, informatica, tecnica > Biologia > Microbiologia

B, Medical research, Biomedical and Life Sciences, Physical Chemistry, Biomedicine, general, Biomedical Research, Membrane Biology, Cell membranes, Membrane Trafficking, Biology—Research, Medicine—Research

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