Proteome Research - Concepts, Technology and Application

Proteomics is a multifaceted, interdisciplinary field which studies the complexity and dynamics of proteins in biological systems. It combines powerful separation and analytical technology with advanced informatics to understand the function of proteins in the cell and in the body. This book provides a clear conceptual description of each facet of proteomics, describes recent advances in technology and thinking in each area, and provides details of how these have been applied to a variety of biological problems. It is written by expert practitioners in the field, from industry, research institutions, and the clinic. It provides junior and experienced researchers with an invaluable proteomic reference, and gives fascinating glimpses of the future of this dynamic field.

Sommario

Ten Years of the Proteome.- Sample Preparation and Prefractionation Techniques for Electrophoresis-Based Proteomics.- Protein Identification in Proteomics.- Quantitation in Proteomics.- One Gene, Many Proteins.- Proteome Imaging.- Data Integration in Proteomics.- Protein-Protein Interactions.- Biomedical Applications of Proteomics.- Proteomics: Where to Next?.

Riassunto

Proteomics is a multifaceted, interdisciplinary field which studies the complexity and dynamics of proteins in biological systems. It combines powerful separation and analytical technology with advanced informatics to understand the function of proteins in the cell and in the body. This book provides a clear conceptual description of each facet of proteomics, describes recent advances in technology and thinking in each area, and provides details of how these have been applied to a variety of biological problems. It is written by expert practitioners in the field, from industry, research institutions, and the clinic. It provides junior and experienced researchers with an invaluable proteomic reference, and gives fascinating glimpses of the future of this dynamic field.

Dettagli sul prodotto

• Con la collaborazione di: R. D. Appel (Editore), R.D. Appel (Editore), D Appel (Editore), R D Appel (Editore), D. F. Hochstrasser (Editore), D.F. Hochstrasser (Editore), K L Williams et al (Editore), M. R. Wilkins (Editore), M.R. Wilkins (Editore), K. L. Williams (Editore), K.L. Williams (Editore)
• Editore: Springer, Berlin
• Lingue: Inglese
• Formato: Tascabile
• Pubblicazione: 01.01.2014
• EAN: 9783642441653
• ISBN: 978-3-642-44165-3
• Pagine: 239
• Dimensioni: 155 mm x 236 mm x 15 mm
• Peso: 409 g
• Illustrazioni: XXII, 239 p.
• Serie: Principles and Practice; Principles and Practice
• Categorie: Scienze naturali, medicina, informatica, tecnica > Biologia > Biochimica, biofisica; C, Medical research, Life Sciences, biochemistry, molecular biology, bioinformatics, Proteomics, Biomedical and Life Sciences, Cellular biology (cytology), Biochemistry, general, Information technology: general issues, Biomedical Research, Cell Biology, Molecular Medicine