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Informationen zum Autor Katja Berginc , University of Ljubljana, Slovenia. Samo Kreft , University of Ljubljana, Slovenia. Klappentext Dietary supplements made from foods! herbs and their constituents are a rapidly growing market sector. Consumers often view food supplements as 'natural' and therefore safe! however supplements are regulated as foods rather than as pharmaceuticals and so are not as closely monitored as may be necessary. With the commercial market in these products growing! this book provides essential research into their safety! efficacy and potential risk of interaction with pharmaceuticals. Following an introductory chapter! part one covers the chemical composition! manufacture and regulation of dietary supplements. Part two looks at the effectiveness of different types of dietary supplement and methods of evaluation. Finally! part three focuses on supplement safety. Zusammenfassung Following an introductory chapter! part one covers the chemical composition! manufacture and regulation of dietary supplements. Part two looks at the effectiveness of different types of dietary supplement and methods of evaluation. Finally! part three focuses on supplement safety. Inhaltsverzeichnis List of contributors Woodhead Publishing Series in Food Science, Technology and Nutrition Introduction Part One: General issues1: Dietary supplement labelling and health claimsAbstract1.1 Introduction: the regulatory situation in the European Union (EU)1.2 Labelling requirements1.3 Nutrition claims1.4 Health claims1.5 Borderline substances: between foods and medicine1.6 ConclusionsAcknowledgementsAppendix: abbreviations2: Good manufacturing practice (GMP) in the production of dietary supplementsAbstract2.1 Introduction2.2 Key issues related to good manufacturing practice/good hygienic practice (GMP/GHP) implementation2.3 Documentation of GMP2.4 Benefits and drawbacks of GMP use in organisations2.5 Summary3: Analysing the composition of fortified foods and supplements: the case of vitaminsAbstract3.1 Introduction3.2 Extraction and purification methods3.3 High performance liquid chromatography (HPLC)3.4 Gas chromatography (GC)3.5 Capillary electrophoresis (CE)3.6 Spectroscopic methods3.7 Microbiological methods3.8 Immunoassays3.9 Other methods3.10 Future trends Part Two: Drug-supplement interactions4: Pharmacokinetic interactions between drugs and dietary supplements: herbal supplementsAbstract4.1 Introduction4.2 Herbals: introduction4.3 Hypericum perforatum (St John's Wort (SJW))4.4 Allium sativum (garlic)4.5 Ginkgo biloba (ginkgo)4.6 Panax ginseng (ginseng), Piper methysticum (kava kava) and Serenoa repens (saw palmetto)4.7 Echinacea purpurea (purple coneflower), Vaccinium macrocarpon (cranberry) and Silybum marianum (milk thistle)4.8 Hydrastis canadensis (goldenseal), Valeriana officinalis (valerian) and Cimicifuga racemosa (black cohosh)4.9 Glycine max (soy), Camellia sinensis (green tea) and Zingiber officinale (ginger)4.10 Morinda citrifolia (noni), Aloe vera (aloe), Vitis vinifera (grape seed) and Curcuma longa (turmeric)4.11 Stevia rebaudiana (stevia), Lepidium meyenii (maca) and Garcinia mangostana (mangosteen)4.12 Summary5: Pharmacokinetic interactions between drugs and dietary supplements: probiotic and lipid supplementsAbstract5.1 Introduction5.2 Probiotics and drug delivery in the colon5.3 Probiotics: summary5.4 Lipids and drug delivery5.5 Lipidic excipients and drug release5.6 Summary: pharmacokinetic drug-lipid interactions6: Pharmacokinetic interactions between drugs and dietary supplements: carbohydrate, protein, vitamin and mineral supplementsAbstract6.1 Introduction6.2 Carbohydrates as dietary supplements6.3 Carbohydrates as pharmaceutical excipients and prodrugs6.4 Carbohydrates: summary6.5 Proteins, peptides, and amino acids6.6 The impact of proteins on drug pharmacokinetics and their use as prodrugs6.7 Proteins: summary6.8 Vitamins6.9 Vi...
Sommario
- List of contributors
- Woodhead Publishing Series in Food Science, Technology and Nutrition
- Introduction
- Part One: General issues
- 1: Dietary supplement labelling and health claims
- Abstract
- 1.1 Introduction: the regulatory situation in the European Union (EU)
- 1.2 Labelling requirements
- 1.3 Nutrition claims
- 1.4 Health claims
- 1.5 Borderline substances: between foods and medicine
- 1.6 Conclusions
- Acknowledgements
- Appendix: abbreviations
- 2: Good manufacturing practice (GMP) in the production of dietary supplements
- Abstract
- 2.1 Introduction
- 2.2 Key issues related to good manufacturing practice/good hygienic practice (GMP/GHP) implementation
- 2.3 Documentation of GMP
- 2.4 Benefits and drawbacks of GMP use in organisations
- 2.5 Summary
- 3: Analysing the composition of fortified foods and supplements: the case of vitamins
- Abstract
- 3.1 Introduction
- 3.2 Extraction and purification methods
- 3.3 High performance liquid chromatography (HPLC)
- 3.4 Gas chromatography (GC)
- 3.5 Capillary electrophoresis (CE)
- 3.6 Spectroscopic methods
- 3.7 Microbiological methods
- 3.8 Immunoassays
- 3.9 Other methods
- 3.10 Future trends
- Part Two: Drug-supplement interactions
- 4: Pharmacokinetic interactions between drugs and dietary supplements: herbal supplements
- Abstract
- 4.1 Introduction
- 4.2 Herbals: introduction
- 4.3 Hypericum perforatum (St John's Wort (SJW))
- 4.4 Allium sativum (garlic)
- 4.5 Ginkgo biloba (ginkgo)
- 4.6 Panax ginseng (ginseng), Piper methysticum (kava kava) and Serenoa repens (saw palmetto)
- 4.7 Echinacea purpurea (purple coneflower), Vaccinium macrocarpon (cranberry) and Silybum marianum (milk thistle)
- 4.8 Hydrastis canadensis (goldenseal), Valeriana officinalis (valerian) and Cimicifuga racemosa (black cohosh)
- 4.9 Glycine max (soy), Camellia sinensis (green tea) and Zingiber officinale (ginger)
- 4.10 Morinda citrifolia (noni), Aloe vera (aloe), Vitis vinifera (grape seed) and Curcuma longa (turmeric)
- 4.11 Stevia rebaudiana (stevia), Lepidium meyenii (maca) and Garcinia mangostana (mangosteen)
- 4.12 Summary
- 5: Pharmacokinetic interactions between drugs and dietary supplements: probiotic and lipid supplements
- Abstract
- 5.1 Introduction
- 5.2 Probiotics and drug delivery in the colon
- 5.3 Probiotics: summary
- 5.4 Lipids and drug delivery
- 5.5 Lipidic excipients and drug release
- 5.6 Summary: pharmacokinetic drug-lipid interactions
- 6: Pharmacokinetic interactions between drugs and dietary supplements: carbohydrate, protein, vitamin and mineral supplements
- Abstract
- 6.1 Introduction
- 6.2 Carbohydrates as dietary supplements
- 6.3 Carbohydrates as pharmaceutical excipients and prodrugs
- 6.4 Carbohydrates: summary
- 6.5 Proteins, peptides, and amino acids
- 6.6 The impact of proteins on drug pharmacokinetics and their use as prodrugs
- 6.7 Proteins: summary
- 6.8 Vitamins
- 6.9 Vitamins: summary
- 6.10 Minerals and oligoelements
- 6.11 Minerals: summary
- 7: Pharmacodynamic interactions between drugs and dietary supplements
- Abstract
- 7.1 Introduction
- 7.2 Vitamins
- 7.3 Minerals
- 7.4 Herbal supplements
- 7.5 Antioxidants
- 7.6 Conclusion
- Part Three: Vitamins, minerals and probiotics as dietary supplements
