Psychiatric Genetics - Methods and Reviews

Psychiatric Genetics provides the reader with a complete view of the methodological problems encountered in psychiatry genetics and proposes solutions to commonly occurring questions. The best European and American specialists have given a thorough review on the advantages and disadvantages of genetic epidemiological methods, the way to choose a genetic marker or a clinical interview and how to ascertain patients, unaffected relatives and controls and what should be the criteria to include a case or a control. New phenotypic methods are described focusing on candidate symptom and endophenotype approaches. Examples coming from cognitive neurosciences, biochemistry, electrophysiology and brain imaging techniques are reviewed. This book will serve as an essential handbook for psychiatrists, psychologists, and geneticists involved in the genetics of psychiatric disorders.

Sommario

Psychiatric Genetics.- Methods in Psychiatric Genetics: Advantages and Limits.- Analytical Methods Applied to Psychiatric Genetics.- Genetic Markers in Psychiatric Genetics.- Clinical Assessment in Psychiatric Genetics.- Genetic Association Studies.- New Phenotypic Approaches.- Searching for Alternative Phenotypes in Psychiatric Genetics.- Intermediate Cognitive Phenotypes Associated with Schizophrenia.- Biochemical Endophenotypes in Personality Disorders.- Electrophysiological Phenotypes.- Brain Imaging as an Approach to Phenotype Characterization for Genetic Studies of Schizophrenia.- Conclusion.- Psychiatric Genetics.

Riassunto

Psychiatric Genetics provides the reader with a complete view of the methodological problems encountered in psychiatry genetics and proposes solutions to commonly occurring questions. The best European and American specialists have given a thorough review on the advantages and disadvantages of genetic epidemiological methods, the way to choose a genetic marker or a clinical interview and how to ascertain patients, unaffected relatives and controls and what should be the criteria to include a case or a control. New phenotypic methods are described focusing on candidate symptom and endophenotype approaches. Examples coming from cognitive neurosciences, biochemistry, electrophysiology and brain imaging techniques are reviewed. This book will serve as an essential handbook for psychiatrists, psychologists, and geneticists involved in the genetics of psychiatric disorders.

Testo aggiuntivo

"...a valiant attempt to make sense of a substantial portion of the methodological aspects of research in psychiatric genetics. Students and senior investigators should both give serious consideration to this book's arguments and advice." - Genes, Brain and Behavior

"...provides a relatively succinct introduction to a range of issues relating to the filed of psychiatric genetics...would be an excellent book for a young researcher about to enter the field of psychiatric genetics and would enable him or her to obtain a rapid overview of methodological issues." - Journal of Medical Genetics

"...great for getting new ideas as well as suggestions for how to deal with practical research questions." - Psychological Medicine

"This book is very useful for students or psychiatrists interested in genetics and how it applies to psychiatric illness. It is one of few in the field to give a comprehensive review of the field." -Doody's Health Sciences Book Review Journal

"Marion Leboyer and Frank Bellivier have put together a very good review of the variety of methods and approaches previously used in this complex area of research and, for this reason, this book provides a useful text for someone entering the field of psychiatric genetics." -Human Genetics

Relazione

"...a valiant attempt to make sense of a substantial portion of the methodological aspects of research in psychiatric genetics. Students and senior investigators should both give serious consideration to this book's arguments and advice." - Genes, Brain and Behavior

"...provides a relatively succinct introduction to a range of issues relating to the filed of psychiatric genetics...would be an excellent book for a young researcher about to enter the field of psychiatric genetics and would enable him or her to obtain a rapid overview of methodological issues." - Journal of Medical Genetics

"...great for getting new ideas as well as suggestions for how to deal with practical research questions." - Psychological Medicine

"This book is very useful for students or psychiatrists interested in genetics and how it applies to psychiatric illness. It is one of few in the field to give a comprehensive review of the field." -Doody's Health Sciences Book Review Journal

"Marion Leboyer and Frank Bellivier have put together a very good review of the variety of methods and approaches previously used in this complex area of research and, for this reason, this book provides a useful text for someone entering the field of psychiatric genetics." -Human Genetics

Dettagli sul prodotto

• Con la collaborazione di: Bellivier (Editore), Bellivier (Editore), Frank Bellivier (Editore), Mario Leboyer (Editore), Marion Leboyer (Editore)
• Editore: Springer, Berlin
• Lingue: Inglese
• Formato: Tascabile
• Pubblicazione: 01.01.2013
• EAN: 9781489938459
• ISBN: 978-1-4899-3845-9
• Pagine: 268
• Dimensioni: 152 mm x 15 mm x 229 mm
• Peso: 410 g
• Illustrazioni: IX, 268 p. 7 illus.
• Serie: Methods in Molecular Medicine; Methods in Molecular Medicine
• Categorie: Scienze naturali, medicina, informatica, tecnica > Medicina > Branche cliniche; C, Medicine, Psychiatry