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Zusatztext ...a well-crafted book for graduate students and cancer researchers who wish to learn more about the key concepts and pathways involved in the rapidly advancing field of cancer biology. Klappentext A thorough yet concise account of cancer biology, this book emphasises the cellular and molecular mechanisms involved in the transformation of normal into malignant cells, the invasiveness of cancer cells into host tissues, and the metastatic spread of cancer cells in the host organism. It also defines the fundamental pathophysiological changes that occur in tumour tissue and in the host animal or patient. The approach throughout the book is to discuss the historicaldevelopment of a field, citing the key experimental advances to the present day, and to evaluate the current evidence that best supports or rules out concepts of the molecular and cellular mechanisms regulating cancer cell behaviour. For all the areas of fundamental cancer research, an effort hasbeen made to relate basic research findings to the clinical disease states. The book is well illustrated with schematic diagrams and actual research data to demonstrate points made in the text, and there is an extensive, up-to-date bibliography. Zusammenfassung Presenting an account of cancer biology, this book emphasises the cellular and molecular mechanisms involved in the transformation of normal into malignant cells, the invasiveness of cancer cells into host tissues, and the metastatic spread of cancer cells in the host organism.
