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"This book is devoted to all of the emerging areas of biomaterials and biodevices, including therapeutic agents, molecular targeting, and diagnostic imaging capabilities. The authors provide a comprehensive view of cutting-edge research on advanced materials for healthcare technology and applications. The book is written for scientists, researchers, and clinicians from diverse backgrounds across chemistry, physics, materials science and engineering, medical science, pharmacy, biotechnology, and biomedical engineering"--Provided by publisher.
Sommario
Preface xv
Part 1: Cutting-edge Biomaterials 1
Frontiers for Bulk Nanostructured Metals in Biomedical Applications 3
T.C. Lowe and R.Z. Valiev
1.1 Introduction to Nanostructured Metals 3
1.2 Nanostructured Metals as Biomaterials for Medical Applications 10
1.3 Summary and Conclusions 29
Acknowledgment 30
References 30
2 Stimuli-responsive Materials Used as Medical Devices in Loading and Releasing of Drugs 53
H. Iván Meléndez-Ortiz and Emilio Bucio
2.1 Introduction 54
2.2 Classification of Materials for Bioapplications 55
2.3 Responsive Polymers in Controlled Drug Delivery 56
2.4 Types of Medical Devices 60
2.5 Materials Used in Medical Devices 62
2.6 Stimuli-responsive Polymers Used in Medical Devices 65
2.7 Infections Associated with Medical Devices 68
Acknowledgements 72
References 73
3 Recent Advances with Liposomes as Drug Carriers 79
Shravan Kumar Sriraman and Vladimir P. Torchilin
3.1 Introduction 80
3.2 Passive Targeting of Liposomes 83
3.3 Actively Targeted Liposomes 88
3.4 Multifunctional Liposomes 95
3.5 Conclusions and Future Directions 98
References 101
4 Fabrication, Properties of Nanoshells with Controllable Surface Charge and its Applications 121
Parul Khurana, Sheenam Thatai and Dinesh Kumar
4.1 What is Nanotechnology? 122
4.2 Nanomaterials and Their Uses 122
4.3 Classification of Nanomaterials 124
4.4 Nanoparticles 126
4.5 Nanocomposites Material 128
4.6 Spherical Silica Particles 129
4.7 Silver Nanoparticles 132
4.8 Gold Nanoparticles 134
4.9 SiO2@Ag and SiO2@Au Core-shell Nanocomposites 137
4.10 Surface Enhanced Raman Scattering 139
4.11 Conclusions 141
Acknowledgements 141
References 141
5 Chitosan as an Advanced Healthcare Material 147
M.A. Jardine and S. Sayed 147
5.1 Introduction 147
5.2 Chemical Modification and Analysis 150
5.3 Chitosan Co-polymers 154
5.4 Nanoparticles 156
5.5 Nanofibres (Electrospinning) 158
5.6 Visualising Nanostructures 160
5.7 Biomedical Applications of Chitosan 163
5.8 Conclusion 175
References 175
6 Chitosan and Low Molecular Weight Chitosan: Biological and Biomedical Applications 183
Nazma N. Inamdar and Vishnukant Mourya
6.1 Introduction 184
6.2 Biodegradability of Chitin and Chitosan 184
6.3 Biocomapatibility and Toxicology of Chitin and Chitosan 186
6.4 Chitosan as Antimicrobial Agent 187
6.5 Chitosan as Haemostatic Agent 196
6.6 Chitosan as Immunity Modulator 198
6.7 Chitosan as Adjuvant 202
6.8 Chitosan as Wound Healing Accelerator 203
6.9 Chitosan as Lipid Lowering Agent & Dietary Supplement in Aid of Weight Loss 211
6.10 Chitosan as Antioxidant 214
6.11 Conclusion 220
References 221
7 Anticipating Behaviour of Advanced Materials in Healthcare 243
Tanvir Arfin and Simin Fatma
7.1 Introduction 244
7.2 The Evolution of the Bio-advance Materials Fields 246
7.3 Evaluation in Humans 247
7.4 The Natural History of Diseases 248
7.5 Enzyme 249
7.6 Biosensor 259
7.7 Platinum Material Used in Medicine 267
7.8 Antibody 268
7.9 Antibody microarrays 275
7.10 Conclusion 278
References 279
Part 2: Innovative Biodevices 289
Info autore
Ashutosh Tiwari is an Associate Professor at the Biosensors and Bioelectronics Centre, Linköping University, Sweden; Editor-in-Chief,
Advanced Materials Letters; Secretary General, International Association of Advanced Materials; a materials chemist and also a docent in applied physics at Linköping University, Sweden. He has published more than 350 articles, patents, and conference proceedings in the field of materials science and technology and has edited/authored more than fifteen books on the advanced state-of-the-art of materials science. He is a founding member of the Advanced Materials World Congress and the Indian Materials Congress.
Anis N. Nordin received her D.Sc. in computer engineering from George Washington University in 2008. She is now an Assistant Professor in the Department of Electrical and Computer Engineering at the International Islamic University Malaysia, Kuala Lumpur. Her main research interests are in the areas of biosensors, lab-on-chip devices, Analog VLSI, RF-MEMS, surface acoustic wave resonators, and oscillators in particular. She is currently a visiting scholar at the Biosensors and Bioelectronics Center, Linköping University, Sweden.
Riassunto
This cutting-edge book focuses on the emerging area of biomaterials and biodevices that incorporate therapeutic agents, molecular targeting, and diagnostic imaging capabilities The design and development of biomaterials play a significant role in the diagnosis, treatment, and prevention of diseases.
Relazione
"Overall, this is a fascinating series of diverse chapters, with a large range of quality in the presentation and diagram quality, and the reader has to have an extensive knowledge of biochemistry and nanotechnology to really appreciate the cutting edge technology presented in this book." ( Scope , 1 February 2014)
