Caveolins in Cancer Pathogenesis, Prevention and Therapy

Caveolins are important structural proteins of Caveolae, small invaginations of the membrane. They have been shown to play an important role in the pathogenesis of multiple cancers. In this volume, we will mainly focus on the importance of Caveolin-1 in breast, prostate, lung, skin, colon, pancreatic and brain cancers with also a mention of the novel role of Caveolin-3 in breast cancer.

Sommario

Preface.- Local and Distant Effects of Caveolin-1 on Prostate Cancer Progression.- Caveolin-1 in Colon Cancer: the Flexible Connection to Wnt Signaling.- Caveolin-1 and Pancreatic Ductal Adenocarcinoma.- Caveolin-1 in Brain Tumors.- The Role of Caveolin-1 in Skin Cancer.- Caveolins and Tumor Angiogenesis.- Caveolin-1 and Breast Cancer.- Caveolin-1 and Cancer-Associated Stromal Fibroblasts.- Index

Riassunto

Caveolins are important structural proteins of Caveolae, small invaginations of the membrane. They have been shown to play an important role in the pathogenesis of multiple cancers. In this volume, we will mainly focus on the importance of Caveolin-1 in breast, prostate, lung, skin, colon, pancreatic and brain cancers with also a mention of the novel role of Caveolin-3 in breast cancer.

Dettagli sul prodotto

• Con la collaborazione di: Jean-Françoi Jasmin (Editore), Jean-François Jasmin (Editore), Michael P. Lisanti (Editore), Isabelle Mercier (Editore), Michael P Lisanti (Editore)
• Editore: Springer, Berlin
• Lingue: Inglese
• Formato: Tascabile
• Pubblicazione: 09.12.2013
• EAN: 9781493901340
• ISBN: 978-1-4939-0134-0
• Pagine: 124
• Dimensioni: 158 mm x 235 mm x 7 mm
• Peso: 219 g
• Illustrazioni: XII, 124 p.
• Serie: Current Cancer Research; Current Cancer Research
• Categorie: Scienze naturali, medicina, informatica, tecnica > Medicina > Branche non cliniche; B, Medicine, Pharmakologie, Pharmacology, Cancer Research, Biomedical Research, Pharmacology/Toxicology