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It has long been recognized that damage to the mammalian central nervous system may be followed by behavioral recovery, but only re cently has close attention been directed to specific factors which may enhance or retard restitution. This is evident in the rapidly growing number of journal articles and scientific paper sessions dealing with "recovery of function," as well as in the publicity given by the popular press to some of the findings in this field. The present text seeks to examine the foundations of brain lesion research, to review recent material on a number of factors which ap pear to contribute to recovery after brain damage, and to present mod els which have been proposed to account for these effects. In order to best accomplish these goals, a number of key workers in these areas were asked to examine and describe research literatures dealing with specific problems or methodological manipulations associated with brain damage and behavior, using their own experiments and those of others to illustrate important points. In addition, significant interpre tive and theoretical issues were to be evaluated in each chapter.
Sommario
I: The Domain of Brain-Lesion Research.- 1 The Logic of the Lesion Experiment and Its Role in the Neural Sciences.- II: Species Variables.- 2 Generalizations in Neuropsychology.- 3 The Interplay of Experimental and Clinical Approaches in Brain Lesion Research.- III: Anatomical Response to CNS Injury.- 4 Lesion Experiments: Some Anatomical Considerations.- 5 Brain Lesions: Induction, Analysis, and the Problem of Recovery of Function.- IV: Experimental Manipulations and Behavioral Recovery.- 6 Age, Brain Damage, and Performance.- 7 Lesion Momentum and Behavior.- 8 Time and Recovery from Brain Damage.- 9 Testing Procedures and the Interpretation of Behavioral Data.- 10 Subtotal Lesions: Implications for Coding and Recovery of Function.- 11 Pharmacological Modification of Brain Lesion Syndromes.- 12 Environmental Attenuation of Brain-Lesion Symptoms.- 13 Sensory Restriction and Recovery of Function.- V: Accounting for Sparing and Restitution.- 14 Recovery after Brain Damage and the Concept of Localization of Function.- 15 Is Seeing Believing: Notes on Clinical Recovery.
