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Klappentext Certain stable lipid nanoemulsions display a marked capability for rapid active targeting! both to tumors and to certain lesion sites. This category of lipid nanoemulsions contains no phospholipids! no proteins nor peptides! no carbohydrates! and no chemical modification of the lipophilic drugs is required; consequently it avoids various problems reported for earlier versions of targeted nanoemulsions. The book covers in detail the underlying chemical and biochemical principles of stable lipid nanoemulsions as well as many applications in nanomedicine such as targeted chemotherapy. It is in harmony with goals of the current US National Nanotechnology Initiative! which include nanomedical approaches to drug delivery that focus on developing nanoscale particles to improve drug bioavailability i.e. often using targeted nanoparticles for delivering drugs with cell precision and less side effects. Despite the obvious practical importance to various fields including nanomedicine there is currently no comprehensive book available in the literature. The proposed book will effectively fill this gap. Zusammenfassung Covers the underlying chemical and biochemical principles of stable lipid nanoemulsions as well as many potential applications in nanomedicine such as targeted chemotherapy.
Sommario
Selected Chapter Titles Occurrence Of Dilute Gas-In-Liquid Emulsions In Natural Waters Early Work With Aqueous Carbohydrate Gels Characteristic Glycopeptide Fraction Of Natural Microbubble Surfactant Ecological Chemistry Of Microbubble Surfactant Structure Of Predominant Surfactant Components Stabilizing Natural MicrobubblesStable Microbubbles In Physiological Fluids: Competing Hypotheses Concentrated Gas-In-Liquid Emulsions In Artificial MediaI. Demonstration By Laser-Light Scattering Proposed Mechanism Of SelectiveL.C.M. Uptake By Tumor Cells: Role Of Lipoprotein Receptor-Mediated Endocytic Pathways Endocytotic Events Versus Particle Size
