Fatal Attractions: Protein Aggregates in Neurodegenerative Disorders

In this volume are contributions based on a meeting arranged by the WHO and the Fondation IPSEN. The scientists focus on neurodegenerative disorders like Alzheimer's Disease, Chromosome 17-Linked Dementia, Parkinson's Disease and disorders with tauopathies.

Sommario

The Role of ?-Synuclein in Parkinson's Disease: A Biophysical Analogy to A? and Alzheimer's Disease.- Purification of Lewy Bodies and Identification of ? -Synuclein as a Major Component of Lewy Bodies.- Mutational Analysis of Tau in Chromosome 17-Linked Dementia.- Missense and Splice Site Mutations in Tau Associated with FTDP-17: Multiple Pathogenic Mechanisms.- Tau Mutations: Genetics and Pathogenetic Mechanisms.- Tauopathies and ?-Synucleinopathies.- Distinct Tau Gene Mutations Induce Specific Dysfunctions/Toxic Properties in Tau Proteins Associated with Specific FTDP-17 Phenotypes.- Neurodegenerative Disorders with Tauopathies: Mad Tau Diseases?.- Tau Protein: Role in Intracellular Traffic and Development of Cell Polarity.

Dettagli sul prodotto

• Con la collaborazione di: L. Buee (Editore), L. Buée (Editore), L Buee et al (Editore), Y. Christen (Editore), V. M. -Y. Lee (Editore), V.M.-Y. Lee (Editore), Q Trojanowski (Editore), J Q Trojanowski (Editore), J. Q. Trojanowski (Editore), J.Q. Trojanowski (Editore)
• Editore: Springer, Berlin
• Lingue: Inglese
• Formato: Tascabile
• Pubblicazione: 11.10.2010
• EAN: 9783642086496
• ISBN: 978-3-642-08649-6
• Pagine: 140
• Dimensioni: 155 mm x 8 mm x 235 mm
• Peso: 248 g
• Illustrazioni: XII, 140 p.
• Serie: Research and Perspectives in Alzheimer's Disease; Research and Perspectives in Alzheimer's Disease
• Categorie: Scienze naturali, medicina, informatica, tecnica > Medicina > Branche non cliniche; C, Neuroscience, Dementia, Neurosciences, Biomedical and Life Sciences, neurodegenerative disorders, tau protein