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Klappentext Hypertension is one of the leading causes of morbidity and mortality in the western world and is often associated with heart failure, acute coronary syndromes, diabetes, and renovascular disease. Retaining the format that made the previous edition so popular, this second edition of a bestseller presents sumamries of the 2013 ESC/ESH Guidelines, the latest basic science findings, and clinical trial data to provide up-to-date, practical, evidence-based recommendations for treatment and prevention of all forms of hypertension. Copious illustrations, tables, and graphs distill key information and aid clinicians in decision-making. Inhaltsverzeichnis Background, History and Epidemiology Epidemiology of Hypertension; Renata Cifkova The Total Cardiovascular Risk; Claudio Borghi, Arrigo Francesco Giuseppe Cicero, and Ettore Ambrosioni Associated Risk Factors Classical and New Risk Factors; Manolis S. Kallistratos and Athanasios J. Manolis Pulse Pressure as a Cardiovascular Risk Factor; Athanase Benetos Clinical Significance of High Heart Rate in Hypertension; Paolo Palatini and Guido Grassi Obesity and Obstructive Sleep Apnea; Marzena Chrostowska, Anna Szyndler, Jacek Wolf, and Krzysztof Narkiewicz Diabetes Mellitus; Peter M. Nilsson Stress, Psychosocial, and Other Risk Factors in the Hypertensive Patient; Philippe Van De Borne Blood Pressure Variability: Methodological Aspects, Pathophysiological and Clinical Implications; Gianfranco Parati, Juan Eugenio Ochoa, and Grzegorz Bilo Antihypertensive Treatment Strategies; Giuseppe Mancia Ethiological and Pathophysiological Aspects Hemodynamics of Hypertension; Per Omvik and Per Lund-Johansen Genetic Basis of Blood Pressure and Hypertension; Sandosh Padmanabhan, Mark Caulfield, and Anna F. Dominiczak Structural Cardiovascular Changes in Hypertension; Harry A.J. Struijker-Boudier Impaired Autonomic Cardiovascular Control in Hypertension; Guido Grassi, Gianmaria Brambilla, and Gino Seravalle The Renin-Angiotensin-Aldosterone System; Ulrike M. Steckelings and Thomas Unger Etiological and Pathophysiological Aspects of Hypertension: Other Humoral-Endocrine Factors; Michel Burnier Target Organ Damage: Measurements/Clinical Importance Cardiac Damage and Progression to Heart Failure; E. Agabiti Rosei, M.L Muiesan, and R.E. Schmieder Brain Damage; Cristina Sierra and Antonio Coca Large Artery Damage: Measurement and Clinical Importance; Stephane Laurent, and Michel E Safar Small Artery Structure and Function in Hypertension; Anthony M. Heagerty, Sarah B. Withers, Ashley S. Izzard, Adam S. Greenstein, and Reza Aghamohammadzadeh Endothelial Damage: Measurement and Clinical Importance; Lorenzo Ghiadoni, Agostino Virdis, and Stefano Taddei Renal Damage and Hypertension: Mechanisms of Renal End-Organ Damage; Hermann Haller Retinal Changes in Hypertension; Martin Ritt, Enrico Agabiti-Rosei, and Roland E Schmieder BP Measurements and Other Diagnostic Procedures BP Measurements and Other Diagnostic Procedures; Jean-Philippe Baguet, Jean-Michel Mallion, and Denis L. Clement Blood Pressure Response to Acute Physical and Mental Stress; Robert Fagard and Guido Grassi Central Blood Pressure; Cristina Giannattasio and Stephane Laurent The Diagnostic Approach in Uncomplicated and Complicated Hypertension; Athanasios J. Manolis and Costas Tsioufis Therapeutic Aspects Blood Pressure Targets of Antihypertensive Treatment; Giuseppe Mancia and Guido Grassi Interventional Trials in Hypertension: What Have We Learned and What Remains to be Learned? Alberto Zanchetti The Nephroprotective Effect of Antihypertensive Treatment; Luis M. Ruilope and Julian Segura Nonpharmacological Interventions; Stefan Engeli and Jens Jordan Medical Treatment of Hypertension: Monotherapy and Combination Therapy; M. Burnier, G. Wuerzner and B. Waeber Emerging Antihypertensive Drugs; Massimo Volpe and Giuliano Tocci The Polypill; Marie Briet and Michel Azizi Invasive Procedures; Rolan...