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Informationen zum Autor About the editors Dr Blanca Hernández-Ledesma Institute of Food Science Research (CIAL, CSIC-UAM), Madrid, Spain Dr Miguel Herrero Institute of Food Science Research (CIAL, CSIC-UAM), Madrid, Spain Klappentext Part of the IFT Press series, this book reviews the myriad published information on bioactive components derived from marine foods, enabling researchers and product developers to select appropriate functional ingredients for new products.Chapters cover foods and food ingredients from both animal and plant marine sources, focusing on those which demonstrate biological properties and whose constituent compounds have been isolated and identified as potentially active. This book further addresses the biological activities of PUFAs (Polyunsaturated fatty acids), oils, phospholipids, proteins and peptides, fibres, carbohydrates, chitosans, vitamins and minerals, fucoxantin, polyphenols, phytosterols, taurine, amongst others. These components, found in a variety of marine-derived foods, have been demonstrated to have preventative properties with regard to hypertension, oxidative stress, inflammation, cardiovascular diseases, cancer and other human diseases. Extraction methods and analysis techniques are also addressed. Intended for food scientists, food technologists and food engineers in academia, industry and government, this book reviews the substantial quantity of current research in this fast-moving and commercially valuable sector of food and nutrition science. Zusammenfassung The world?s oceans are a vast source of plant and animal foods which contain materials with the potential to be used as functional ingredients. Many such compounds have been identified, isolated, and characterized as being potentially active against various degenerative diseases such as cancer. Inhaltsverzeichnis List of Contributors xvii 1 An Update on the Biomedical Prospects of Marine-derived Small Molecules with Fascinating Atom and Stereochemical Diversity 1 Yvette Mimieux Vaske and Phillip Crews 1.1 Introduction 1 1.2 A view based on atom diversity 11 1.3 A view based on stereochemical diversity 15 1.4 Case studies of chemical probes and chemical probes in the therapeutic discovery pipeline 20 1.5 Conclusion 21 Acknowledgments 21 References 21 2 Antihypertensive Peptides from Marine Sources 27 Roseanne Norris, P¿adraig¿ýn A. Harnedy, and Richard J. FitzGerald 2.1 Introduction 27 2.2 Marine antihypertensive peptides and blood pressure control 28 2.3 Generation of marine antihypertensive peptides 32 2.4 Structure-activity relationships 32 2.5 Bioavailability 33 2.6 In vivo animal studies 35 2.7 In vivo human studies 41 2.8 Marine peptides as antihypertensive ingredients 45 2.9 Conclusion 48 Acknowledgments 48 References 48 3 Bioactive Peptides from Marine Processing Byproducts 57 Maria Hayes and David Flower 3.1 Introduction 57 3.2 Fish muscle proteins: precursors of fish bioactive peptides 58 3.3 Fish meal production 59 3.4 Fish silage production 59 3.5 Traditional fermented fish protein products 60 3.6 Strategies for the generation of bioactive peptides from marine byproducts 60 3.7 Conclusion 66 Acknowledgments 67 References 67 4 Development of Marine Peptides as Anticancer Agents 73 Xiukun Lin and Lanhong Zheng 4.1 Introduction 73 4.2 Peptides that induce apoptosis 73 4.3 Peptides that affect the tubulin-microtubule equilibrium 81 4.4 Peptides that inhibit angiogenesis 83 4.5 Peptides without a known mechanism for their antitumor activity 84 4.6 Conclusion 85 Acknowledgments 86 References 86<...
