Ulteriori informazioni
Informationen zum Autor Vijay Kumar Thakur (Ph.D.) is a Staff Scientist in the School of Mechanical and Materials Engineering at Washington State University, U.S.A. He has published more than 100 research articles, patents and conference proceedings in the field of polymers and materials science and has published ten books and 25 book chapters on the advanced state-of-the-art of polymers/ materials science. He has extensive expertise in the synthesis of polymers (natural/ synthetic), nano materials, nanocomposites, biocomposites, graft copolymers, high performance capacitors and electrochromic materials. Manju Kumari Thakur works in the Department of Chemistry, Himachal Pradesh University, Simla, India. Klappentext Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications.Advances in polymer science and the introduction of new polymers have resulted in the significant development of polymers with unique properties. Different kinds of polymers have been and will be one of the key in several applications in many of the advanced pharmaceutical research being carried out over the globe. This 4-partset of books contains precisely referenced chapters, emphasizing different kinds of polymers with basic fundamentals and practicality for application in diverse pharmaceutical technologies. The volumes aim at explaining basics of polymers based materials from different resources and their chemistry along with practical applications which present a future direction in the pharmaceutical industry. Each volume offer deep insight into the subject being treated. Volume 1: Structure and Chemistry Volume 2: Processing and Applications Volume 3: Biodegradable Polymers Volume 4: Bioactive and Compatible Synthetic/Hybrid Polymers Zusammenfassung Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life. Polymers are either directly available in nature or are chemically synthesized and used depending upon the targeted applications. Inhaltsverzeichnis Preface xvii 1 Gellan as Novel Pharmaceutical Excipient 1 Priya Vashisth, Harmeet Singh, Parul A. Pruthi and Vikas Pruthi 1.1 Introduction 1 1.2 Structural Properties of Gellan 2 1.3 Physiochemical Properties of Gellan 4 1.3.1 Gelling Features and Texture Properties 4 1.3.2 Rheology 6 1.3.3 Biosafety and Toxicological Studies 6 1.4 Pharmaceutical Applications of Gellan 7 1.4.1 Gellan-Based Pharmaceutical Formulations 7 1.4.2 Role of Gellan Excipients in Drug Delivery and Wound Healing 11 1.5 Conclusion and Future Perspectives 16 References 16 2 Application of Polymer Combinations in Extended Release Hydrophilic Matrices 23 Ali Nokhodchi, Dasha Palmer, Kofi Asare-Addo, Marina Levina and Ali Rajabi-Siahboomi 2.1 Extended Release Matrices 23 2.1.1 Polymers Used in ER Matrices 24 2.1.2 Water-Soluble (Hydrophilic) Polymers 24 2.1.3 Water-Insoluble Polymers 24 2.1.4 Fatty Acids/Alcohols/Waxes 25 2.2 Polymer Combinations Used in ER matrices 25 2.2.1 Compatibility and Miscibility of Polymers 25 2.2.2 Combination of Non-Ionic Polymers 26 2.3 Combination of Non-Ionic with Ionic Polymers 27 2.4 Combinations of Ionic Polymers 27 2.5 Other Polymer Combinations 28 2.6 Effect of Dissolution Method (Media) on Drug Release from ER Matrices Containing Polymer Combinations 28 2.7 Main Mechanisms of Drug-Polymer and/or Polymer-Polymer Interaction in ER Formulations 30 2.8 Summary and Conclusions 39 References 40 ...
