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The hemostasis laboratory has a vital role in the diagnosis of patients with familial and acquired hemorrhagic and thrombotic disorders. This work covers international guidelines for testing, the development of international standard materials, management of hemostasis testing from the laboratory to the point of care and molecular genetic testing.
List of contents
Foreword, Frits R. Rosendaal.
1. General Quality Planning in the Hemostasis Laboratory, John D. Olson.
2. Hemostasis Test Validation, Performance and Reference Intervals: International Recommendations and Guidelines, Richard A. Marlar.
3. International Standards in Hemostasis, Trevor W. Barrowcliffe.
4. Sample Integrity and Preanalytical Variables, Dorothy M. Adcock.
5. Internal Quality Control in the Hemostasis Laboratory, Steve Kitchen, F. Eric Preston, John D. Olson.
6. External Quality Assessment in Hemostasis: Its Importance and Significance, F. Eric Preston, Steve Kitchen, Alok Srivastava.
7. Initial Evaluation of Hemostasis: Reagent and Method Selection, Wayne L. Chandler.
8. Point-of-Care Testing in Hemostasis. Chris Gardiner, Samuel Machin, Ian Mackie.
9. Assay of Factor VIII and Other Clotting Factors, Steve Kitchen, F. Eric Preston.
10. Application of Molecular Genetics to the Investigation of Inherited Bleeding Disorders, Stefan Lethagen, Marianne Schwartz, Lars Bo Nielson.
11. Standardisation of D-dimer Testing, Guido Reber, Philippe de Moerloose.
12. Diagnostic Assessment of Platelet Function, Paquita Nurden, Alan Nurden.
13. Laboratory Evaluation of von Willebrand Disease: Phenotypic Analysis, Emmanuel J. Favaloro.
14. Laboratory Analysis of von Willebrand Disease: Molecular Analysis, Anne Goodeve, Ian Peake.
15. Dilemmas in Heritable Thrombophilia Testing, Isobel Walker, Ian Jennings .
16. Evaluation of Antiphospholipid Antibodies, Michael Greaves.
17. Monitoring Heparin Therapy, Marilyn Johnston.
18. Monitoring Oral Anticoagulant Therapy, Armando Tripodi.
19. Monitoring New Anticoagulants, Elaine Gray, Trevor W. Barrowcliffe.
20. Detecting and Quantifying Functional Inhibitors in Hemostasis, Bert Verbruggen, Irena Nováková, Waander van Heerde
