Bioinformatics

Zusatztext "...The book and the attached web links together give readers a rich resource of topics covered..." (Statistical Methods in Medical Research! Vol.14! No.1! 2005) Informationen zum Autor Andreas D. Baxevanis! Ph.D. is the Deputy Director for Intramural Research and the Director of the Computational Genomics Program at the National Human Genome Research Institute! National Institutes of Health. He is currently the editor-in-chief of Current Protocols in Bioinformatics! senior editor of Molecular Cancer Therapeutics! and associate editor of Proteins: Structure! Function! and Bioinformatics. His involvement in educational activities include teaching bioinformatics at The Johns Hopkins University! serving as adjunct faculty at Boston University! lecturing in numerous courses! and developing materials intended to facilitate the use of genomic sequence data. He is the recipient of the Bodossaki Foundation's 2000 Academic Prize in Medicine and Biology.Dr. B. F. Francis Ouellette is Director of the University of British Columbia Bioinformatics Centre and Director for the Canadian Genetic Disease Network (CGDN) Bioinformatics Facility! where he coordinates the Canadian Bioinformatics Workshop series. His research includes work on the Biomolecular Interaction Network Database (BIND)! development of gene prediction tools! and use of comparative genomics approaches to help identify human genes. Dr. Ouellette has worked on yeast genome sequencing and analysis! and has previously served as GenBank coordinator at the National Center for Biotechnology Information (NCBI)! NIH. Klappentext Von der Datenbank zum prädiktiven oder komparativen Algorithmus: Dieser weltweit geschätzte Klassiker! jetzt in dritter Auflage! führt Sie in alle wichtigen Konzepte der Bioinformatik ein. Noch ansprechender gestaltet - mehrfarbig! in größerem Format und mit abgesetzten "Kästen" - nimmt der hervorragend lesbare und aktuelle Text eine Spitzenposition unter den einschlägigen Lehrwerken für Biologen ein. In dieser Auflage wird noch mehr Wert auf realitätsnahe Übungsaufgaben gelegt. Viele neue Aufgaben sind hinzugekommen; Lösungen können vom zugehörigen Webserver (www.wiley.com/bioinformatics) abgerufen werden. Nützliche Zugaben: ein Glossar und ein Anhang mit Codebeispielen. Zusammenfassung Reviews of the Second Edition "In this book! Andy Baxevanis and Francis Ouellette... have undertaken the difficult task of organizing the knowledge in this field in a logical progression and presenting it in a digestible form. And they have done an excellent job. Inhaltsverzeichnis Foreword (Lee Hood).Preface.Contributors.PART ONE: BIOLOGICAL DATABASES.1. Sequence Databases (Rolf Apweiler).2. Mapping Databases (Peter S. White and Tara C. Matise).3. Information Retrieval from Biological Databases (Andreas D. Baxevanis).4. Genomic Databases (Tyra G. Wolfsberg).PART TWO: ANALYSIS AT THE NUCLEOTIDE LEVEL.5. Predictive Methods Using DNA Sequences (Enrique Blanco and Roderic Guigó).6. Predictive Methods Using RNA Sequences (David Mathews and Michael Zuker).7. Sequence Polymorphisms (James C. Mullikin and Stephen T. Sherry).PART THREE: ANALYSIS AT THE PROTEIN LEVEL.8. Predictive Methods Using Protein Sequences (Yanay Ofran and Burkhard Rost).9. Protein Structure Prediction and Analysis (David Wishart).10. Intermolecular Interactions and Biological Pathways (Gary D. Bader and Anton J. Enright).PART FOUR: INFERRING RELATIONSHIPS.11. Assessing Pairwise Sequence Similarity: BLAST and FASTA (Andreas D. Baxevanis).12. Creation and Analysis of Protein Multiple Sequence Alignments (Geoffrey J. Barton).13. Sequence Assembly and Finishing Methods (Nancy F. Hansen! Pamela Jacques Thomas and Gerard G. Bouffard).14. Phylogenetic Analysis (Fiona S. L. Brinkman).15. Computational Approaches in Comparative Genomics (Andreas D. Baxevanis).16. Using DNA Microarrays t...

List of contents

Foreword (Lee Hood).

Preface.

Contributors.

PART ONE: BIOLOGICAL DATABASES.

1. Sequence Databases (Rolf Apweiler).

2. Mapping Databases (Peter S. White and Tara C. Matise).

3. Information Retrieval from Biological Databases (Andreas D. Baxevanis).

4. Genomic Databases (Tyra G. Wolfsberg).

PART TWO: ANALYSIS AT THE NUCLEOTIDE LEVEL.

5. Predictive Methods Using DNA Sequences (Enrique Blanco and Roderic Guigó).
6. Predictive Methods Using RNA Sequences (David Mathews and Michael Zuker).

7. Sequence Polymorphisms (James C. Mullikin and Stephen T. Sherry).

PART THREE: ANALYSIS AT THE PROTEIN LEVEL.

8. Predictive Methods Using Protein Sequences (Yanay Ofran and Burkhard Rost).

9. Protein Structure Prediction and Analysis (David Wishart).

10. Intermolecular Interactions and Biological Pathways (Gary D. Bader and Anton J. Enright).

PART FOUR: INFERRING RELATIONSHIPS.

11. Assessing Pairwise Sequence Similarity: BLAST and FASTA (Andreas D. Baxevanis).

12. Creation and Analysis of Protein Multiple Sequence Alignments (Geoffrey J. Barton).

13. Sequence Assembly and Finishing Methods (Nancy F. Hansen, Pamela Jacques Thomas and Gerard G. Bouffard).

14. Phylogenetic Analysis (Fiona S. L. Brinkman).

15. Computational Approaches in Comparative Genomics (Andreas D. Baxevanis).

16. Using DNA Microarrays to Assay Gene Expression (John Quackenbush).

17. Proteomics and Protein Identification (Mark R. Holmes, Kevin R. Ramkissoon and Morgan C. Giddings).

PART FIVE: DEVELOPING TOOLS.

18. Using Perl to Facilitate Biological Analysis (Lincoln D. Stein).

Appendices.

Glossary. Index.

Report

"...an outstanding achievement and will be a sound resource forbioengineers, cellular and molecular biotechnologists, andbioinformatists." ( Annals of Biomedical Engineering , June2006)
"...does an excellent job of tracking developments andproviding an account that will be accessible to working biologists.This should be on the bookshelf of every molecular biologist."( The Quarterly Review of Biology , December 2005)

"...fully delivers on its promise of providing a useful andpractical guide...I found it to be the most useful book onbioinformatics I have seen and recommend it very highly." ( ASMNews , September 2005)

"...not only an excellent guidebook ... but also asupreme teaching and reference material."( ChemBioChem , 2005; Vol. 6, 6)

"...not only an excellent guidebook for bioinformatics usersbut also...a supreme teaching and reference material."( ChemBioChem , July 4, 2005)

"...the most updated bioinformatics book that offers expertinsights into cutting-edge tools of modern computational biologyand stands out from many current texts on the subject."( American Journal of Human Biology , May/June 2005)

"...The book and the attached web links together givereaders a rich resource of topics covered..." ( StatisticalMethods in Medical Research , Vol.14, No.1, 2005)

Product details

• Authors: Andreas Baxevanis, Andreas D. Baxevanis, Mark Boguski, B. F. Francis Ouellette, B.F. Francis Ouellette
• Assisted by: Andreas D. Baxevanis (Editor), Andrea D Baxevanis (Editor), F Francis Ouellette (Editor), B. F. Fr. Ouellette (Editor), B. F. Francis Ouellette (Editor), B.F.Francis Ouellette (Editor)
• Publisher: Wiley, John and Sons Ltd
• Languages: English
• Product format: Hardback
• Released: 19.11.2004
• EAN: 9780471478782
• ISBN: 978-0-471-47878-2
• No. of pages: 560
• Dimensions: 220 mm x 290 mm x 25 mm
• Series: Wiley-Interscience; Wiley-Interscience
• Subjects: Natural sciences, medicine, IT, technology; Bioinformatik