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Scientists now understand that cancer is a genetic disease and cutting -edge molecular therapies are making their way from the laboratory into clinical practice. Introduction to Oncogenes and Molecular Cancer Medicine provides the physician with a solid understanding of molecular biology and its applications for the diagnosis and treatment of cancer. The book reviews the basic molecular principles and the basic principles of cancer medicine, including controls of cell growth and senescence, carcinogenesis, tumorogenesis, and epidemiology. The second part of the book gives clinical examples to demonstrate the basic science principles, including chapters on leukemia, colon cancer, and breast cancer. A chapter on molecular diagnostics and screening plus a chapter on new molecular anti-cancer therapies give the reader a look at current cutting-edge therapies as well as as the future of molecular cancer medicine. A useful glossary defines new terminology at-a-glance. Introduction to Oncogenes and Molecular Cancer Medicine is for all physicians seeking a better understanding of the modern molecular principles of cancer medicine. Written in a user-friendly, conversational format, this text will be welcomed by all physicians eager to sharpen their own understanding of molecular cancer medicine as well as to help them provide patients with balanced information on the advances and limitations of current treatment options.
List of contents
I Basic Principles of Molecular Biology.- 1 Molecular Biology of Cells.- 2 Cell Growth and Senescence.- 3 Oncogenes: Control of Cell Growth and Senescence.- 4 Tumor Suppressor Genes.- 5 Multiple Steps in the Molecular Causes of Cancer.- II Clinical Examples of Molecular Oncology.- 6 Molecular Diagnostics.- 7 Leukemia and Lymphoma.- 8 Colon Cancer.- 9 Squamous Cell Carcinoma of the Uterine Cervix.- 10 Breast Cancer.- 11 Molecular Anticancer Therapies.- Conclusions.
Summary
Providing the physician with a solid understanding of molecular biology and its applications for the diagnosis and treatment of cancer, this book reviews the basic molecular and other principles of cancer medicine, including controls of cell growth and senescence, carcinogenesis, tumorogenesis, and epidemiology.
