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Klappentext Animal experiments have contributed much to our understanding of mechanisms of disease and are important for determining new therapies. This volume reviews the latest research and developments in this field. * Discusses new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields PRAISE FOR THE SERIES "Full of interest not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--British Medical Journal Zusammenfassung Animal experiments have contributed much to our understanding of mechanisms of disease and are important for determining various therapies. This title reviews the research and developments in this field. It discusses different discoveries! approaches! and ideas. It is suitable for researchers involved in molecular biology and related fields. Inhaltsverzeichnis 1. Modelling cancers in Drosophila Dr. Lucas Waltzer 2. Modeling human prostate cancer in mice Dr. Fen Wang 3. The Drosophila heart: a model system for the genetics of cardiac disease and senescence Dr. Robert Wessells 4. Dissection of cardiovascular development and disease pathways in zebrafish John D. Mably 5. Transgenic mouse models of human cardiovascular and blood diseases Dr. Simon J. Conway 6. 800 Facets of Retinal Degeneration Dr. Andrew C. Zelhof 7. Towards a better understanding of human eye disease: insights from the zebrafish, Danio rerio Dr. Jeffrey M Gross 8. Mouse models of retinal disease Dr. Paul N. Baird 9. Eating on the Fly: Studying Metabolic Diseases in Drosophila melanogaster Dr David Tree 10. Mouse models of selected inborn errors of metabolism William J. Craigen 11. Modeling disoders of mitochondrial fatty acid metabolism in the mouse Dr. Eric Goetzman 12. Watching Worms Whither: Modeling Neurodegeneration in C. elegans Dr. Benjamin Wolozin 13. Demise of the Flies?: Why Drosophila Models Still Matter George R. Jackson 14. Utility of zebrafish to late-onset neurology: A developmental model coming of age W. Ted Allison 15. Genetic Mouse Models of Neurodegenerative Diseases Darren J. Moore ...
List of contents
1. Modelling cancers in Drosophila
Dr. Lucas Waltzer
2. Modeling human prostate cancer in mice
Dr. Fen Wang
3. The Drosophila heart: a model system for the genetics of cardiac disease and senescence
Dr. Robert Wessells
4. Dissection of cardiovascular development and disease pathways in zebrafish
John D. Mably
5. Transgenic mouse models of human cardiovascular and blood diseases
Dr. Simon J. Conway
6. 800 Facets of Retinal Degeneration
Dr. Andrew C. Zelhof
7. Towards a better understanding of human eye disease: insights from the zebrafish, Danio rerio
Dr. Jeffrey M Gross
8. Mouse models of retinal disease
Dr. Paul N. Baird
9. Eating on the Fly: Studying Metabolic Diseases in Drosophila melanogaster
Dr David Tree
10. Mouse models of selected inborn errors of metabolism
William J. Craigen
11. Modeling disoders of mitochondrial fatty acid metabolism in the mouse
Dr. Eric Goetzman
12. Watching Worms Whither: Modeling Neurodegeneration in C. elegans
Dr. Benjamin Wolozin
13. Demise of the Flies?: Why Drosophila Models Still Matter
George R. Jackson
14. Utility of zebrafish to late-onset neurology: A developmental model coming of age
W. Ted Allison
15. Genetic Mouse Models of Neurodegenerative Diseases
Darren J. Moore
Report
PRAISE FOR THE SERIES
"Full of interest not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal
