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Klappentext This book presents an in-depth overview on the topic of protein synthesis, covering all areas of protein science, including protein targeting, secretion, folding, assembly, structure, localization, quality control, degradation, and antigen presentation. Chapters also include sections on the history of the field as well as summary panels for quick reference. Numerous color illustrations complement the presentation of material. This book is an essential reference for anyone in biochemistry and protein science, as well as an excellent textbook for advanced students in these and related fields. Zusammenfassung Presents an in-depth overview on the topic of protein synthesis and covers various areas of protein science! including protein targeting! secretion! folding! assembly! structure! localization! quality control! degradation! and antigen presentation. This book also includes sections on the history of the field and summary panels for quick reference. Inhaltsverzeichnis Methods in Protein Targeting, Translocation and Transport Targeting Sequences Protein Export in Bacteria Protein Sorting at the Membrane of the Endoplasmic Reticulum Membrane Protein Insertion into Bacteial Membranes and Endoplasmic Reticulum Disulfide Bond Formation in Prokaryotes and Eukaryotes The Unfolded Protein Response Protein Quality Control in the Export Pathway: The Endoplasmic Reticulum and its Cytoplasmic Proteasome Connection Translocation of Proteins into Mitochondria The Import and Sorting of Protein into Chloroplasts Import of Proteins into Peroxisomes Nucleocytoplasmic Transport Protein Transport to the Yeast Vacuole The Secretory Pathway Vesicular Transport Conclusion/Perspective
List of contents
Methods in Protein Targeting, Translocation and Transport
Targeting Sequences
Protein Export in Bacteria
Protein Sorting at the Membrane of the Endoplasmic Reticulum
Membrane Protein Insertion into Bacteial Membranes and Endoplasmic Reticulum
Disulfide Bond Formation in Prokaryotes and Eukaryotes
The Unfolded Protein Response
Protein Quality Control in the Export Pathway: The Endoplasmic Reticulum and its Cytoplasmic Proteasome Connection
Translocation of Proteins into Mitochondria
The Import and Sorting of Protein into Chloroplasts
Import of Proteins into Peroxisomes
Nucleocytoplasmic Transport
Protein Transport to the Yeast Vacuole
The Secretory Pathway
Vesicular Transport
Conclusion/Perspective
Report
"...Dalbey et al. have summed up what has happened so far in a rapidly moving field of modern cellular biochemistry."
--EUROPEAN JOURNAL OF CHEMICAL BIOLOGY, 2003
"Overall this book provides good summaries of what we know about how proteins are moved between intracellular compartments and how we have studied this problem. Students or anyone wanting to know more about protein trafficking, particularly protein translocation across membranes, will find it a useful guide." --CELL, 2002
