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Informationen zum Autor Robert M. Tanguay is the author of Aging, Cancer and Age-related Disease: Common Mechanisms?, Volume 1197, published by Wiley. Klappentext This volume recognizes the rapidly expanding research linking aging, age-related diseases, and the delicate balance between neurodegeneration and cancer. Wide perspectives on aging are covered, ranging from metabolic and cellular interventions in aging, oxidative stress resistance, protein folding and quality control, as well as the troublesome relationship between prevention of chaperonopathies and the risk for cancer.Key Features:* Explores current research linking aging, age-related diseases, neurodegeneration, and cancer.* Includes papers presented at 13th Congress of the Association of Biomedical Gerontology* Part of the Annals of the New York Academy of Sciences seriesThis book is ideal for Graduate students and researchers in the fields of biomedical gerontology, cell and molecular biology, neuroscience, and oncology.NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas.ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member. Zusammenfassung This volume recognizes the rapidly expanding research linkingaging, age-related diseases, and the delicate balance betweenneurodegeneration and cancer. Inhaltsverzeichnis Why aging research?: the moral imperative to retard human aging / Colin Farrelly Age-related behavioral changes in Drosophila / Konstantin G. Iliadi and Gabrielle L. Boulianne A screen for genes involved in respiration control and longevity in Schizosaccharomyces pombe / Antoine E. Roux Targeting the age-related occurrence, removal, and accumulation of molecular damage by hormesis / Suresh I.S. Rattan Biological significance of protein modifications in aging and calorie restriction / Akihiro Nakamura [and others] Ascorbate improves metabolic abnormalities in Wrn mutant mice but not the free radical scavenger catechin / Michel Lebel [and others] Evaluating the role of p38 MAP kinase in growth of Werner syndrome fibroblasts / Terence Davis [and others] Decreasing the aging velocity in industry workers / U¿lo Kristjuhan Mitochondrial pathways governing stress resistance, life, and death in the fungal aging model Podospora anserina / Heinz D. Osiewacz [and others] Protection from aging by small chaperones : a trade-off with cancer? / Genevie¿ve Morrow [and others] HSPB1, actin filament dynamics, and aging cells / Bindi M. Doshi, Lawrence E. Hightower and Juliet Lee Chaperonopathies of senescence and the scrambling of interactions between the chaperoning and the immune systems / Alberto J.L. Macario [and others] Exogenous mammalian extracellular HSP70 reduces endotoxin manifestations at the cellular and organism levels / Elena Rozhkova [and others] Cellular aging and centrosome aberrations / Susumu Ohshima and Atsushi Seyama Synchronization of posttranslational modifications during aging: time is a crucial biological dimension / Andre¿ Schrattenholz, Vukic¿ S¿os¿kic¿ and Karlfried Groebe Molecular bridging of aging and cancer: a CARF link / Caroline T. Cheung, Sunil C. Kaul and Renu Wadhwa Emerging role of the MORF/MRG gene family in various biological processes, including aging / Meizhen Chen, Kaoru Tominaga and Olivia M. Pereira-Smith Transcriptome analysis and tumor suppressor requirements of STAT5-induced senescence / Fre¿de¿rick A. Mallette [and others] Major heat shock protein Hsp72 ...
