Fr. 70.00

Fundamentals of Medicinal Chemistry

English · Paperback / Softback

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Zusatztext "...provides a concise introduction to the chemistry of therapeutically active compounds! written in a readable and accessible style..." (www.organische-chemie.ch! 19/01/2004) Informationen zum Autor Gareth Thomas is a lecturer at the University of Portsmouth. Klappentext Medizinische Chemiker beschäftigen sich mit der Erforschung therapeutisch aktiver Verbindungen. Eine Einführung in dieses Gebiet, das mittlerweile auch vielfach im Grundstudium behandelt wird, bietet Ihnen dieser handliche Band. Neben Grundlagen werden viele Anwendungsbeispiele behandelt; Übungsaufgaben (teils mit Lösungen) erleichtern das Umsetzen des Stoffes in die Praxis. Zusammenfassung Provides an introduction to the chemistry of therapeutically active compounds. This title reviews the structures and nomenclature of the more common classes of naturally occurring compounds found in biological organisms. An overview of medicinal chemistry is followed by chapters covering the discovery and design of drugs. Inhaltsverzeichnis Preface.Acknowledgements.Abbreviations/Acronyms.1. Biological Molecules.2. An Introduction to Drugs and Their Action.3. An Introduction to Drug Discovery.4. The SAR and QSAR Approaches to Drug Design.5. Computer Aided Drug Design.6. Combinatorial Chemistry.7. Selected Examples of Drug Action at some Common Target Areas.8. Pharmacokinetics.9. Drug Metabolism.10. An Introduction to Lead and Analogue Syntheses.11. Drug Development and Production.Appendix 1. Sickle-cell Anaemia.Appendix 2. Bacteria.Appendix 3. Cell Membranes.Appendix 4. Receptors.Appendix 5. Transfer through Membranes.Appendix 6. Regression Analysis.Appendix 7. Enzymes.Answers to Questions.Selected Further Reading.Index.

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