Cancer and Development

A number of molecular pathways and cellular processes are essential for normal vertebrate development that has been implicated in cancer initiation and progression. This volume includes the insights into the importance of developmental pathways for tumorigenesis by the leaders in the field of cancer genetics and developmental biology.

List of contents

1. Childhood Cancer and Developmental Biology: A Crucial Partnership - Dyer, MA


2. Stem Cells in Brain Tumor Development - Parada, L


3. MDM2 and MDMX in Cancer and Development - Marine, J-C


4. The Connections between Neural Crest Development and Neuroblastoma- Lahti, J


5. Rb1, development, and cancer - Goodrich. D


6. Genetic alterations targeting lymphoid development in acute lymphoblastic leukemia - Mullighan, C


7. Myogenesis and rhabdomyosarcoma: The Jekyll and Hyde of skeletal muscle - Saab, R, Spunt, S and Skapek, S


8. Medulloblastoma - Roussel, MF and Hattan, ME


9. Rethinking Pediatric Gliomas as Developmental Brain Abnormalities - Gutmann, DH


10. Tumor macrophages: protective and pathogenic roles in cancer development - Murray, P. J.

Product details

• Authors: Michael Dyer
• Assisted by: Michael Dyer (Editor)
• Publisher: ELSEVIER SCIENCE BV
• Languages: English
• Product format: Hardback
• Release: 01.04.2011, delayed
• EAN: 9780123809162
• ISBN: 978-0-12-380916-2
• No. of pages: 384
• Series: Academic Press; Current Topics in Developmental Biology; Current Topics in Developmenta; Current Topics in Developmental Biology; Current Topics in Developmenta
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine; SCIENCE / Life Sciences / Developmental Biology, Developmental biology