Genome Duplication

Zusatztext "...an accessible work that undergraduate students in their first molecular genetics class can easily read and understand. At the same time! this book has much to offer graduate students and researchers in the field. Many excellent tables summarize the information in each chapter. The volume also includes a glossary! clear illustrations! and chapter references." - Klevickis! C.A.!CHOICE! April 2011"This book will be very informative for a wide audience-population biologists! molecular epidemiologists! and ecology/evolution instructors! as well as graduate students."- The Quarterly Review of Biology Informationen zum Autor DePamphilis, Melvin; Bell, Stephen Klappentext This comprehensive and readable overview provides an excellent starting point for undergraduate and graduate students. Using model organisms from the three domains of life (Bacteria! Archaea! and Eukarya)! Genome Duplication describes the principal molecular mechanisms of DNA replication and shows how the process is linked to cell division. This approach allows the authors to shed insight into how genome duplication has evolved! and how its regulation is relevant to the understanding and treatment of human disease! especially cancer. Zusammenfassung Using model organisms from the three domains of life (Bacteria, Archaea, and Eukarya), this title explains the principle molecular mechanisms of DNA replication and shows how the process is linked to cell division. It is suitable for undergraduate and graduate students. Inhaltsverzeichnis 1. Genomes 2. Three Domains of Life 3. Replication Forks 4. Replication Proteins: Leading-Strand Synthesis 5. Replication Proteins: Lagging-Strand Synthesis 6. Termination 7. Chromatin Assembly, Cohesion, and Modification 8. Replicons 9. Replication Origins 10. Origin Paradigms 11. Initiation 12. Cell Cycles 13. Checkpoints 14. Human Disease 15. Evolution of Cellular Replication Machines ...

Product details

• Authors: Stephen Bell, Stephen D. Bell, Stephen D. (Oxford University Bell, Melvin Depamphilis, Melvin (National Institute of Child Health and Human Development DePamphilis, Melvin L. DePamphilis, DePamphilis Melvin
• Publisher: Taylor & Francis Ltd.
• Languages: English
• Product format: Paperback / Softback
• Released: 01.09.2010
• EAN: 9780415442060
• ISBN: 978-0-415-44206-0
• No. of pages: 450
• Subjects: Natural sciences, medicine, IT, technology > Biology > Genetics, genetic engineering; SCIENCE / Life Sciences / General, SCIENCE / Life Sciences / Biology, SCIENCE / Life Sciences / Molecular Biology, SCIENCE / Life Sciences / Cell Biology, SCIENCE / Life Sciences / Genetics & Genomics, molecular biology, Cellular biology (cytology), Genetics (non-medical)