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Informationen zum Autor Dr. Udo H. Brinker, University Professor; Head of Research Group for Physical Organic Chemistry and Structural Chemistry, Institute of Organic Chemistry, University of Vienna; and Research Professor of Chemistry at State University of New York at Binghamton, NY, USA. Dr. Jean-Luc Mieusset, University Assistant, Institute of Organic Chemistry, University of Vienna. Klappentext The inclusion of small guest molecules within suitable host compounds results in constrained systems that imbue novel properties upon the incarcerated organic substrates. Supramolecular tactics are becoming widely employed and this treatise spotlights them. Often, the impact of encapsulation on product formation is substantial. The use of constrained systems offers the means to steer reactions along desired pathways. A broad overview of various supramolecular approaches aimed to manipulate chemical reactions are featured.The following topics are covered in detail:- general concepts governing the assembly of the substrate with the reaction vessel- preparation of molecular reactors- stabilization of reactive intermediates- reactions in water, in organic solvents, and in the solid state- photochemical reactions- reactions with unusual regioselectivityMolecular Encapsulation: Organic Reactions in Constrained Systems is an essential guide to the art of changing the outcome and the selectivity of a chemical reaction using nano-sized reaction vessels. It will find a place on the bookshelves of students and researchers working in the areas of supramolecular chemistry, nanotechnology, organic and pharmaceutical chemistry, and materials science as well. Zusammenfassung The inclusion of small guest molecules within suitable host compounds results in constrained systems that imbue novel properties upon the incarcerated organic substrates. Supramolecular tactics are becoming widely employed and this treatise spotlights them. Often, the impact of encapsulation on product formation is substantial. Inhaltsverzeichnis Preface page. List of Contributors. 1 Reaction Control by Molecular Recognition - A Survey from the Photochemical Perspective ( Cheng Yang, Chenfeng Ke, Yu Liu, and Yoshihisa Inoue ). 1.1 Introduction. 1.2 Photochemical Reactions Mediated by Macrocyclic Compounds. 1.3 Photochemical Reactions with Biomolecules. 1.4 Photochemical Reactions with Confined Cages Based on Inorganic and Organic-Inorganic Hybrid Materials. 1.5 Photochemical Reactions with other Artificial Hosts. 1.6 Photoreaction Control by External Variants. 1.7 Conclusions. 2 Cyclodextrins ( Ronald Breslow ). 2.1 Introduction. 2.2 Acylations of the Cyclodextrins by Bound Substrates. 2.3 Catalytic Reactions in Cyclodextrin Cavities: Aromatic Substitution. 2.4 Other Solvents than Water. 2.5 Catalytic Reactions Produced by Cyclodextrins With Covalently Attached Catalytic Groups. 2.6 Binding by Cyclodextrins and their Dimers and Trimers. 2.7 Mimics of Enzymes that Use Thiamine Pyrophosphate as a Co-Enzyme. 2.8 Aldol Condensations Catalysed by Cyclodextrin Derivatives. 2.9 Mimics of Enzymes Using Coenzyme B12 as a Cofactor. 2.10 Mimics of Cytochrome P-450. 3 Cyclodextrins as Molecular Reactors ( Christopher J. Easton and Hideki Onagi ). 3.1 Introduction. 3.2 Regiocontrolled Electrophilic Aromatic Substitutions. 3.3 Catalysis of Hydrolytic Reactions. 3.4 A Molecular Reactor for the Synthesis of Indigoid Dyes. 3.5 Manipulation of Cycloadditions. 3.6 Conclusion. 4 Reactions Mediated by Cyclodextrins ( Keiko Takahashi ). 4.1 Introduction. 4.2 The Inclusion Phenomena of Cyclodextrins. 4.3 Origin of Microvessels as Molecular Flasks. 4.4 O...
