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Informationen zum Autor TETSUO SATOH is Professor Emeritus of Chiba University and Director of the Research Institute at NPO-HAB Research Organization. He received the 2007 International Union of Toxicology (IUTOX) Merit Award in recognition of his significant international contributions to the field of toxicology. Dr. Satoh is also the recipient of the 2010 Education Award of the Society of Toxicology in the United States. Professor Satoh has had a long and prestigious career as one of the international leaders in the science of toxicology. He has published approximately 310 scientific articles and thirty reviews. He has organized a number of important international, national and regional scientific congresses, including several sponsored by IUTOX, ASIATOX, as well as the Japanese Society of Toxicology. RAMESH C. GUPTA is Professor and Head of the Toxicology Department at Murray State University. He is the former president of the American Academy of Veterinary and Comparative Toxicology (AAVCT), and has more than 300 publications to his credit, along with fifty book and encyclopedia chapters as well as five major books. Currently, he holds active membership in ten professional societies and serves as a guest editor of the journal Toxicology and Applied Pharmacology. Dr. Gupta is the recipient of the Distinguished Researcher Award in 2006 from Murray State University, and is internationally known for his research in the field of pesticides and experimental brain research. Klappentext An important reference source for today's pesticide researchersBesides being a nuisance, pests are infamous for damaging food supplies and spreading deadly diseases. Currently, the most effective means of preventing and controlling their onslaught is through the use of pesticides. Unfortunately, this practice is a necessity that does not come without risk.This thorough, authoritative reference on the most common classes of pesticides and their toxicity examines how their widespread and indiscriminate use has significantly jeopardized the earth's environment as well as the health of man and animal alike. Anticholinesterase Pesticides presents a broad international perspective that looks at studies from around the world, with particular focus on organophosphate (OP) and carbamate (CM) pesticides, and explores the harmful consequences of long- and short-term exposure in people from different occupational settings on a country-by-country basis as well as on an overall global basis. Some of the issues discussed in this eye-opening book include:* Exclusive coverage of the topic of epidemiology* A look at the integration of aspects from the following: metabolism, epidemiology, toxicology, biochemistry, and molecular biology* A full examination of the fundamental science and mechanisms behind pesticide chemicals, as well as biomonitoring* Coverage of regulatory issues and therapeutic interventionFrom measuring a pesticide's toxic effects to looking at ways to solve this unchecked environmental hazard, Anticholinesterase Pesticides takes on the task of thoroughly investigating a chemical compound that is very much needed-and very little understood. Zusammenfassung The use of pesticides is unavoidable. Insidious pests destroy our food and serve as vehicles to spread disease. Pesticides, however, do not come without risks. This authoritative reference is the first comprehensive reference on the neurotoxicity, metabolism, and epidemiology of pesticides. Inhaltsverzeichnis Foreword ( Donald J. Ecobichon ). Section I. 1. Introduction ( Tetsuo Satoh, Ramesh C. Gupta ). Section II: Metabolism and Mechanisms. 2. ACETYLCHOLINESTERASE AND ACETYLCHOLINE RECEPTORS: BRAIN REGIONAL HETEROGENEITY ( Haruo Kobayashi, Tadahiko Suzuki, Fumiaki Akahori and Tetsuo Satoh ). 3. GENOMIC IMPLICATIONS OF ANTICHOLINESTERASE SENSITIVITIES ( Jonathan E. ...
