Drug Design - Cutting Edge Approaches

"Drug Design: Cutting Edge Approaches" focuses on how cutting-edge methods can accelerate drug design. The topics include target finding, virtual screening, informatics in lead optimization, and in silico pharokinetic profiling. Several worked examples show the power of these methods. TOC:Target Finding * Virtual Screening * Informatics in Lead Optimization* In Silico Pharmokinetic Profiling

List of contents

Introduction; High-Throughput X-Ray Crystallography for Drug Discovery; Bioinformatics in Drug Design: a GPCR case study; Virtual Screening of Virtual Libraries - an Efficient Strategy for Lead Generation; Virtual Techniques for Lead Optimisation; The Impact of Physical Organic Chemistry on the Control of Drug-like Properties; Mutagenesis and Modelling Highlight the Critical Nature of the TM2-loop-TM3 region of biogenic amine GPCRS; Computational Vaccine Design; Subject Index.

Summary

Providing details of state-of-the-art research, Drug Design: Cutting Edge Approaches will be invaluable to all drug discovery scientists.

Product details

• Authors: D. R. Flower, Darren R. Flower, Royal Society of Chemistry
• Assisted by: D. R. Flower (Editor), Darren R Flower (Editor), Darren R. Flower (Editor)
• Publisher: RSC Publishing
• Languages: English
• Product format: Hardback
• Released: 31.12.2019
• EAN: 9780854048168
• ISBN: 978-0-85404-816-8
• No. of pages: 202
• Dimensions: 156 mm x 234 mm x 13 mm
• Weight: 463 g
• Series: Special Publications; Special Publication; Special Publications; Special Publication
• Subject: Natural sciences, medicine, IT, technology > Chemistry > Theoretical chemistry