Using Mass Spectrometry for Drug Metabolism Studies

Informationen zum Autor Walter A. Korfmacher Zusammenfassung Offers information on various findings regarding biomarkers and metabolomics. This book presents an overview of the entire drug discovery process, including various developments in molecular research. Inhaltsverzeichnis Strategies and Techniques for Bioanalytical Assays as Part of New Drug Discovery. The Drug Discovery Process: From Molecules to Drugs. PK Principles and PK/PD Applications. Mass Spectrometry for In Vitro ADME Screening. Metabolite Identification Strategies and Procedures. Reactive Metabolite Screening and Covalent-Binding Assays. Fast Metabolite Screening in a Discovery Setting. Fast Chromatography with UPLC and Other Techniques. Supercritical Fluid Chromatography–Mass Spectrometry. Biomarkers of Efficacy and Toxicity: Discovery and Assay. Imaging Mass Spectrometry for Small Molecules. MALDI IMS for Proteins and Biomarkers. Ambient Ionization Methods and Their Early Applications in ADME Studies. Pharmaceutical Applications of Accelerator Mass Spectrometry.

Product details

• Authors: Walter A. Korfmacher, Walter A. (Schering-Plough Research In Korfmacher
• Assisted by: Walter A. Korfmacher (Editor), Walter A. (Schering-Plough Research Institute Korfmacher (Editor), Korfmacher Walter A. (Editor)
• Publisher: Taylor & Francis Ltd.
• Languages: English
• Product format: Hardback
• Released: 03.11.2009
• EAN: 9781420092202
• ISBN: 978-1-4200-9220-2
• No. of pages: 452
• Subjects: Natural sciences, medicine, IT, technology > Chemistry > Theoretical chemistry; SCIENCE / Chemistry / Industrial & Technical, SCIENCE / Chemistry / General, MEDICAL / Pharmacology, SCIENCE / Chemistry / Analytic, Biology, life sciences, Spectrum analysis, spectrochemistry, mass spectrometry, Pharmaceutical technology, Pharmaceutical chemistry and technology