Leucocyte Adhesion

Regulation of cell adhesion is important for immune system function. This title provides a comprehensive approach to specific topics relevant to the study of cellular membranes. It presents a review of the developments in leucocyte adhesion.

List of contents

1. Membrane composition and properties
Lipid rafts (open)
Membrane tethers
(R Waugh, Rochester)
Microvilli
(JY Shao, Wash U)
Whole cell deformation
(D Khismatullin, Tulane)

2. Adhesion molecules
Integrin activation
(M. Shimaoka, Harvard)
Cytoskeletal anchoring
(Fred Pavalko, Iowa)
No tile yet
(Alon, Weizman)
Catch bonds
(Cheng Zhu, Georgia Tech and Roger McEver, OMRF)
Modeling adhesion
(Pospieszalska/Ley, LIAI)
Factors limiting the onset of bond formation at cell interfaces
(R Waugh, Rochester)

3. Active role of endothelial cells
Adhesive platforms
(O. Barreiro, Madrid)
Migratory cups, podosomes
(Chris Carman, Beth Israel)
PECAM recycling
(WA Muller, Northwestern)

4. Methods
1. FRET
(Minsoo Kim, Rochester)
2. Flow chambers
(Simon SI at UC Davis)

Product details

• Authors: Klaus Ley, Klaus (EDT) Ley
• Assisted by: Klaus Ley (Editor), Klaus (University of Virginia Health System Ley (Editor), Ley Klaus (Editor)
• Publisher: ELSEVIER SCIENCE BV
• Languages: English
• Product format: Hardback
• Released: 24.11.2009
• EAN: 9780123749093
• ISBN: 978-0-12-374909-3
• No. of pages: 300
• Series: Current Topics in Membranes; Current Topics in Membranes
• Subjects: Natural sciences, medicine, IT, technology > Biology > Biochemistry, biophysics; SCIENCE / Life Sciences / Biochemistry, biochemistry