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This long-awaited first book on this exciting new field in organic and supramolecular chemistry explains the fundamentals as well as possible applications of DCC. Authored by the "Who's Who" of DCC it spans the whole range of topics: catalysts, sensors, polymers, ligands, receptors, concluding with a look at future developments and perspectives.
All set to become the standard text in the field, this one-stop reference contains everything organic, catalytic, polymer, physical and biochemists need to know.
List of contents
HISTORY AND PRINCIPLES OF DYNAMIC COMBINATORIAL CHEMISTRY
Introduction
History
Exercising Control over a DCL to Influence Species Distribution
Designing a Dynamic Combinatorial System
Conclusions
THE PRACTICE OF DYNAMIC COMBINATORIAL LIBRARIES: ANALYTICAL CHEMISTRY, EXPERIMENTAL DESIGN, AND DATA ANALYSIS
Introduction
Analytical Methods
Experimental Design
Data Analysis
Conclusions
DEVELOPMENT OF SYNTHETIC RECEPTORS USING DYNAMIC COMBINATORIAL CHEMISTRY
Introduction
Experimental Considerations
Selected Examples
Conclusion
DYNAMIC COMBINATORIAL CHEMISTRY FOR CATALYTIC APPLICATIONS
Introduction
Dynamic Combinatorial Approaches to Cage Catalysts
Dynamic Combinatorial Approaches to Transition Metal Catalysts
Conclusions
DYNAMIC COMBINATORIAL CHEMISTRY: LIGANDS FOR BIOMOLECULES
Ligand Discovery
DCC Strategies in Targeting Biological Systems
Dynamic Diversity Generation for Biological Systems
Applications of DCC in Biological Systems
Conclusions and Future Prospects
POLYMERS FORMED BY DYNAMIC COMBINATORIAL CHEMISTRY
Introduction
Dynamics in Polymers
Biasing Composition by Molecular Recognition
Conclusions and Outlook
ANALYTICAL APPLICATIONS OF DYNAMIC COMBINATORIAL CHEMISTRY
Introduction
Fluorescent Sensors
Colorimetric Sensors
Molecular Timers
Conclusions
TRENDS AND PERSPECTIVES
Introduction
Dynamic Combinatorial Libraries as Molecular Networks
Perspectives
About the author
Joost Reek received his PhD in 1996 in the group of Prof. R.J.M. Nolte in the area of supramolecular chemistry. In January 1998 he became lecturer (senior lecturer in 2003) in the group of Prof. Van Leeuwen with research activities focusing on transition metal catalysis. He received numerous grants among which prestigious VICI grant. In 2005 became a young member of royal Dutch academy of sciences (KNAW) and in 2006 he was appointed full professor at the University of Amsterdam.
Sijbren Otto received his Ph.D. degree from the University of Groningen in the Netherlands. After one year in the United States as a postdoctoral researcher with Prof. Steven L. Regen (Lehigh University, Bethlehem, Pennsylvania) he received a Marie Curie Fellowship and moved to the University of Cambridge where he worked for two years with Prof. Jeremy K. M. Sanders on dynamic combinatorial libraries. He started his independent research career in 2001 as a Royal Society University Research Fellow.
Summary
This long-awaited first book on this exciting new field in organic and supramolecular chemistry explains the fundamentals as well as possible applications of DCC. Authored by the "Who's Who" of DCC it spans the whole range of topics: catalysts, sensors, polymers, ligands, receptors, concluding with a look at future developments and perspectives.
All set to become the standard text in the field, this one-stop reference contains everything organic, catalytic, polymer, physical and biochemists need to know.
