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Informationen zum Autor Nathan S. Mosier is an Associate Professor in the Department of Agricultural and Biological Engineering and the Laboratory of Renewable Resources Engineering at Purdue University. Mosier was also an NSF IGERT PhD Fellow from 2000-2002 at the Innovation Realization Laboratory in Krannert School of Management, and has authored case studies based on commercialization experiences for use in entrepreneurship and/or technology commercialization business school curricula. Michael R. Ladisch , a member of the National Academy of Engineering, is Distinguished Professor in the Department of Agricultural and Biological Engineering at the Weldon School of Biomedical Engineering, Director of the Laboratory of Renewable Resources Engineering at Purdue University, and Chief Technology Officer at Mascoma Corporation, a cellulosic biofuels company. He is coeditor of several books on biotechnology, including Harnessing Biotechnology for the 21st Century and Protein Purification, and is the author of Wiley's Bioseparations Engineering text. Klappentext A unique resource for the next generation of biotech innovatorsEnabling everything from the deciphering of the human genome to environmentally friendly biofuels to lifesaving new pharmaceuticals, biotechnology has blossomed as an area of discovery and opportunity. Modern Biotechnology provides a much-needed introduction connecting the latest innovations in this area to key engineering fundamentals. With an unmatched level of coverage, this unique resource prepares a wide range of readers for the practical application of biotechnology in biopharmaceuticals, biofuels, and other bioproducts.Organized into fourteen sections, reflecting a typical semester course, Modern Biotechnology covers such key topics as:* Metabolic engineering* Enzymes and enzyme kinetics* Biocatalysts and other new bioproducts* Cell fusion* Genetic engineering, DNA, RNA, and genes* Genomes and genomics* Production of biopharmaceuticals* Fermentation modeling and process analysisTaking a practical, applications-based approach, the text presents discussions of important fundamentals in biology, biochemistry, and engineering with relevant case studies showing technology applications and manufacturing scale-up. Written for today's wider, more interdisciplinary readership, Modern Biotechnology offers a solid intellectual foundation for students and professionals entering the modern biotechnology industry. Zusammenfassung Biotechnology introduces students in science, engineering, or technology to the basics of genetic engineering, recombinant organisms, wild-type fermentations, metabolic engineering and microorganisms for the production of small molecule bioproducts. Inhaltsverzeichnis 1. BIOTECHNOLOGY. Introduction. The Directed Manipulation of Genes Distinguishes the New Biotechnology From Prior Biotechnology. Growth of The New Biotechnology Industry Depends on Venture Capital. Submerged Fermentations Are the Industry's Bioprocessing Cornerstone. Oil Prices Affect Parts Of the Fermentation Industry. Growth of the Antibiotic/Pharmaceutical Industry. The Existence of Antibiotics Was Recognized in 1877. Penicillin Was The First Antibiotic Suitable for Human Systemic Use. Genesis of the Antibiotic Industry. Other Antibiotics Were Quickly Discovered After the Introduction of Penicillin. Discovery and Scale-up Are Synergistic in the Development of Pharmaceutical Products. The Success of the Pharmaceutical Industry In Research, Development and Engineering Contributed to Rapid Growth but Also Resulted in Challenges. Growth of the Amino Acid/Acidulant Fermentation Industry. Production of Monosodium Glutamate (MSG via Fermentation. The Impact of Glutamic Acid Bacteria on Monosodium Glutamate Cost Was Dramatic. Auxotrophic and Regula...
List of contents
1. Biotechnology.
2. New Biotechnology.
3. Bioproducts and Biofuels.
4. Microbial Fermentations.
5. Modeling and Simulation.
6. Aerobic Bioreactors.
7. Enzymes.
8. Enzyme Kinetics.
9. Metabolism.
10. Biological Energetics.
11. Metabolic Pathways.
12. Genetic Engineering: DNA, RNA, and Genes.
13. Metabolic Engineering.
14. Genomes and Genomics.
Report
"Regardless, if one is specifically interested in quantitative microbial biotechnology, then this is a great, concise, and informative Textbook." (The Quarterly Review of Biology, 1 December 2011)
