Handbook of Glycomics

Klappentext The Handbook of Glycomics provides the first comprehensive overview of the emerging field of glycomics, defined as the study of all complex carbohydrates in an organism or cell ("the glycome"). Beginning with analytic approaches and bioinformatics, this work provides a detailed discussion of relevant databases, data integration, and analysis. It then moves on to a discussion of specific model organism and pathogen glycomes followed by therapeutic approaches to human disorders of glycosylization. Structure and function of glycomes are included along with state-of-the-art technologies and systems approaches to the analysis of glycans. Zusammenfassung Offers a comprehensive overview of the field of glycomics! defined as the study of complex carbohydrates in an organism or cell ('the glycome'). This work discusses specific model organism and pathogen glycomes followed by therapeutic approaches to human disorders of glycosylation. It includes discussions of proteomics! mass spectrometry! and NMR. Inhaltsverzeichnis Introduction to Glycomics SECTION 1: Glycoconjugate Structural Analysis 1. Glycoproteomics: N-glycan Analysis 2. Glycoproteomics: O-glycan Analysis 3. Glycosaminoglycans 4. Isotopic Labeling of Glycans for Quantitative Glycomics SECTION II: Glycotranscriptomics 5. Glycotranscriptomics SECTION III: Protein-Glycan Interactions 6. Glycan Arrays 7. Chromatographic and Mass Spectrometric Techniques SECTION IV: Glycobioinformatics 8. Integration of Glycomics Knowledge and Data 9. KEGG GLYCAN for integrated analysis of pathways, genes, and glycan structures 10. European Glycomics Portal SECTION V: Glycomes 11. Glycomics of the Immune System 12. Mouse and Human 13. Drosophila 14. Malaria 15. Parasitic Worms SECTION VI: Disease Glycomes 16. Cancer Glycomics 17. An Introduction to Human Disorders of Glycosylation 18. Summary ...

Product details

• Authors: Richard D. Cummings, J. Michael Pierce
• Assisted by: Richard D Cummings (Editor), Richard D. Cummings (Editor), Richard D. (Emory University School of Medicine Cummings (Editor), Cummings Richard D. (Editor), J Michael Pierce (Editor), J. Michael Pierce (Editor), J. Michael (University of Georgia Pierce (Editor), Michael J. Pierce (Editor), Pierce J. Michael (Editor)
• Publisher: ELSEVIER SCIENCE BV
• Languages: English
• Product format: Hardback
• Released: 21.08.2009
• EAN: 9780123736000
• ISBN: 978-0-12-373600-0
• No. of pages: 512
• Series: Academic Press
• Subjects: Natural sciences, medicine, IT, technology > Biology > Biochemistry, biophysics; SCIENCE / Life Sciences / Biochemistry, biochemistry, CARBOHYDRATES