Read more
Informationen zum Autor David D. Cunningham, PhD , is a Volwiler Associate Research Fellow at Abbott Diagnostics. Julie A. Stenken, PhD , is Professor and 21st Century Chair of Proteomics at the University of Arkansas Klappentext Leading experts explain the many approaches to in vivo glucose sensing and point to new directions in researchSoon, people with diabetes will be able to depend on reliable, user-friendly in vivo glucose sensing systems to monitor their blood sugar levels. This volume brings readers fully up to date with recently commercialized in vivo sensing systems as well as current efforts to develop new and improved systems. The authors, leading pioneers and researchers in the field, include an MD and both academic and industrial researchers. Together, they review the many approaches to solving the "glucose sensing problem," helping readers apply the latest technology and advance their own research efforts.Following an introductory chapter that sets forth the promise and challenges of glucose sensing, the book explores:* Understanding and controlling the wound-healing response to facilitate implanted sensors* State-of-the-technology implants, including electrochemical sensors and microdialysis devices* New approaches to develop non-invasive, optical-based methods for measuring in vivo glucoseChapters describe both analytical approaches and in vivo results, underscoring the need for a deep understanding of sensing technology as well as human anatomy and physiology. Throughout the book, detailed figures help readers better understand how and why various sensor systems work. In addition, color reproductions of tissue and histological slides draw attention to important features of the body tissue/sensor interface.From established technologies to the most recent research advances, this book explains the current state of knowledge, sets forth the challenges, and points to new breakthroughs for in vivo glucose sensing. Zusammenfassung In Vivo Glucose Sensing is a key reference for scientists and engineers working on the development of glucose sensing technologies for the management of diabetes and other medical conditions. It discusses the analytical chemistry behind the strategies currently used for measuring glucose in vivo. Inhaltsverzeichnis Preface. Contributors. Chapter 1. Introduction to the Glucose Sensing Problem (George S. Wilson and Yanana Zhang). Chapter 2. The Macrophage in Wound Healing Surrounding Implanted Devices (Marisha L. Godek and David W. Grainger). Chapter 3. Strategies to Overcome Biological Barriers to Biosensing (W. Kenneth Ward and Heather M. Duman). Chapter 4. A Window to Observe the Foreign Body Reaction to Glucose Sensors (Milan T. Makale and Jared B. Goor). Chapter 5. Commercially Available Continuous Glucose Monitoring Systems (Timothy Henning). Chapter 6. Membrane-Based Separations Applied to In Vivo Glucose Sensing-Microdialysis and Ultrafiltration Sampling (Julie A. Stenken). Chapter 7. Transdermal Microfluidic Continuous Monitoring Systemsn (David D. Cunningham). Chapter 8. Redundant Arrays and Next-Generation Sensors (Becky L. Clark and Michael V. Pishko). Chapter 9. Nitric Oxide-Releasing Subcutaneous Glucose Sensors (Heather S. Paul and Mark H. Schoenfisch). Chapter 10: Fluorescence-Based Glucose Sensors (Mike McShane and Erich Stein). Chapter 11. The Use of Single-Walled Carbon Nanotubes for Optical Glucose Detection (Paul W. Barone and Michael S. Strano). Chapter 12. Introduction to Spectroscopy for Noninvasive Glucose Sensing (Wei-Chuan Shih, Kate L. Bechtel, Michael S. Feld, Mark A. Arnold and Gary W. Small). Chapter 13. Near-Infrared Spectroscopy for Noninvasive Glucose Sensing (Mark A. Arnold, Jonathon T. Olesberg and Gary W. Small). Chapter 14. Noninvasive Glucose Sensing with Raman Spectroscopy (Wei-Chua...
