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Informationen zum Autor Manel Esteller Klappentext Epigenetic changes are essential to normal development! but these changes can also cause problems including the disabling of genes that suppress tumors. At present! more than a dozen drugs that target epigenetic changes are in clinical trials. Epigenetics in Biology and Medicine offers a comprehensive overview of epigenetics! both in normal functions and disease states. This book presents contributions from international experts! addressing both theoretical and methodological issues. It discusses cell biology and the role of epigenetics in human! animal! and plant diseases. The text also covers DNA methylation inhibitors! histone modifications! and epigenomics! as well as the impact that diet has on epigenetic changes. Zusammenfassung Anomalous epigenetic patterns touch many areas of study including biomedical, scientific, and industrial. With perspectives from international experts, this resource offers an overview of epigenetics, which bridge DNA information and function by regulating gene expression without modifying the DNA sequence itself. Inhaltsverzeichnis An Introduction to Epigenetics. Epigenetics and DNA Methylation. Epigenetics! Histones! and Chromatin. Epigenetics and Cancer: DNA Methylation. Epigenetics and Cancer: Histone Modifications. Epigenetic Drugs: DNA Methylation Inhibitors. Epigenetic Drugs: Histone Deacetylase Inhibitors. Epigenetics and Mental Health Disorders. Epigenetics and Cardiovascular Disease. Epigenetics and Imprinting. Epigenetics and Immunity. Epigenetics and Cloning. Epigenetics! Plants! and Agriculture. Epigenetics and Cancer: Chromatin Remodelling. Epigenetics and Its Genetic Syndromes. Epigenetics! Environment! and Diet. Epigenetics! Epigenomes! and Epigenomics.
