Gene Profiles in Drug Design

Featuring contributions from leaders in a number of fields, this volume explores the processes and technologies that yield gene profile-based drugs. Each chapter focuses on one component or step in the process of translating abstract gene profiles into tangible new drugs. The first part of the text compares the advantages and pitfalls of various methods that have been used to generate gene profiles. The next section discusses current uses of gene profiles in drug design, including lead identification. The book concludes with a look at emerging technologies that use gene profiles to design high specificity drugs.

List of contents

 A Perspective on the Future Clinical Impact of Genetic Diagnosis and Gene-Based Drug Therapies for Patient Health. Virally Encoded MicroRNA (miRNA): Candidates for Gene Silencing. Development of Gene-Profile-Responsive Antisense Agents. Gene Profiles in Drug Development: Applications in Target Identification, Biomarker Discovery, and Compound Characterization. Gene Profiles and Cancer. RNA Viruses and RNA-Based Drugs: A Perfect Match for RNA Delivery and the Identification of Candidate Therapeutic Target Inflammatory Molecules. Ethical Considerations for a Genetic Future in Diagnosis and Drug Development.

About the author

Brett A. Lidbury, Suresh Mahalingam

Summary

Explores the processes and technologies that yield gene profile-based drugs. This book focus on components or steps in the process of translating abstract gene profiles into tangible new drugs. It compares the advantages and pitfalls of various methods that have been used to generate gene profiles.

Product details

• Authors: Brett A. (EDT)/ Mahalingam Lidbury, Brett A. (University of Canberra Lidbury, Brett A. Mahalingam Lidbury
• Assisted by: Brett A. Lidbury (Editor), Brett A. (University of Canberra Lidbury (Editor), Lidbury Brett A. (Editor), Suresh Mahalingam (Editor), Suresh (University of Canberra Mahalingam (Editor), Mahalingam Suresh (Editor)
• Publisher: Taylor & Francis Ltd.
• Languages: English
• Product format: Hardback
• Released: 10.07.2008
• EAN: 9780849337338
• ISBN: 978-0-8493-3733-8
• No. of pages: 168
• Dimensions: 159 mm x 235 mm x 19 mm
• Subjects: Natural sciences, medicine, IT, technology > Biology > General, dictionaries; Medical research, MEDICAL / Pharmacy, SCIENCE / Chemistry / General, MEDICAL / Biochemistry, SCIENCE / Life Sciences / Genetics & Genomics, biochemistry, Pharmaceutical technology, Genetics (non-medical), Pharmaceutical chemistry and technology