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Informationen zum Autor Professor Richard Fine , Professor and Chairman, Department of Paediatrics, State University of New York, USA Dr Steve Webber , Division of Cardiology, Children's Hospital of Pittsburgh, USA Dr William Harman , Associate Professor of Paediatrics, Harvard Medical School, Boston, USA Klappentext Pediatric Solid Organ Transplantation is a comprehensive and succinct text on all aspects of pediatric solid organ transplantation. It provides a ready source of reference, to both the basic science and organ specific surgical technique and after care. This second edition has been extensively updated in light of recent developments in this rapidly advancing area. The only textbook devoted to the field of pediatric transplantation A definitive reference for all those interested in improving the care and quality of life of children undergoing solid organ transplantation Section on immunosuppression has been expanded by four chapters to include sections on; - mechanisms of action - therapies for the sensitized patient - post-transplant lymphoproliferative disorders - organ toxicities of immunosuppressive therapy A new section has been added on the many topics related to quality of life that effect survivors of pediatric transplantation International editorial and contributor team represents a wide geographical range and contains both recognized leaders and emerging experts Whether you are an established sub-specialist in pediatric transplantation, a transplant surgeon, or a pediatric specialist in a related area, this book will answer all your questions about care of the pediatric patient before, during, and after transplantation. Zusammenfassung Pediatric Solid Organ Transplantation is a comprehensive and succinct text on all aspects of pediatric solid organ transplantation. It provides a ready source of reference! to both the basic science and organ specific surgical technique and after care. Inhaltsverzeichnis Section 1 Immunology and Genetics. 1 The Immune Response to Organ Allografts. Manikkam Suthanthiran. 2 Allorecognition Pathways. Nader Najafian and Mohamed H. Sayegh. 3 Costimulation. Elizabeth Ingulli and David M. Briscoe. 4 The HLA System and Histocompatibility Testing for Organ Transplantation. René J. Duquesnoy. 5 Gene Polymorphisms and Pharmacogenomics. Robyn Temple-Smolkin, Gilbert J. Burckart and Adriana Zeevi. 6 Genomics and Proteomics as Research Tools. Elaine S. Mansfield and Minnie M. Sarwal. 7 Tolerance: A Review of its Mechanisms in the Transplant Setting. Alan D. Salama. Section 2 Immunosuppression and its Complications. 8 Mechanisms of Action of Immunosuppressive Agents. Alan M. Krensky . 9 Induction and Maintenance Immunosuppression. William E. Harmon. 10 Novel Immunosuppressants. Flavio Vincenti and Ryutaro Hirose. 11 Therapies for the Allosensitized Patient. Alice Peng and Stanley C. Jordan. 12 Infections Post-Transplantation. Michael Green and Marian G. Michaels. 13 Post-Transplant Lymphoproliferative Disorders and Malignancy. Steven A. Webber and Michael Green . 14 Organ Toxicities. Vikas R. Dharnidharka, Carlos E. Araya and Mark R. Benfield. Section 3 Kidney Transplantation . 15 Historical Notes. Vassilios E. Papalois and John S. Najarian . 16 Recipient Characteristics. Sharon M. Bartosh. 17 Evaluation of the Candidate. Uptal D. Patel and Susan E. Thomas . 18 Donor Evaluation, Surgical Technique and Perioperative Management. Zoran Vukcevic, Demetr...
