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Klappentext The first volume of its kind in the field! Therapeutic Microbiology explores the potential and actual uses of the many methods for altering the microbiotas of humans and animals: probiotics! prebiotics! synbiotics! bacteriophages! and replacement therapy. It describes the biological principles underlying the manipulation of the indigenous microbiota and the biology of the effector organisms that have been utilized for this purpose. The many microbes that can potentially be used therapeutically and prophylactically are discussed at length. Zusammenfassung * First book devoted to the field of therapeutic microbiology * Serves as an important reference source for clinicians and researchers in both human and veterinary medicine and in dentistry * Contains the latest knowledge on this dramatically growing field. Inhaltsverzeichnis Table of Contents 1. INTRODUCTION 1 Introduction! Mary Ellen Sanders 2. BASIC BIOLOGY 2.1. The Indigenous Microbiota 2 Role of the Indigenous Microbiota in Health and Disease! Gerald W. Tannock 2.2. Biology of Effector Organisms for Probiotic and Replacement Therapy 3 Lactobacilli! Covadonga Barbes 4 Bifidobacteria: the Model Human Gut Commensal! Marco Ventura! Francesca Turroni! Angela Ribbera! Elena Foroni! and Douwe van Sinderen 5 Saccharomyces spp.! Xinhua Chen and Ciaran P. Kelly 6 Streptococci as Effector Organisms for Probiotic and Replacement Therapy! John R. Tagg! Jeremy P. Burton! Philip A. Wescombe! and Chris N. Chilcott 7 Escherichia coli! Michael Schultz 8 Formulation! Administration! and Delivery of Probiotics! Kasipathy Kailasapathy 2.3. Prebiotics and Functional Carbohydrates 9 Introduction to Prebiotics! Helena M. R. T. Parracho! Delphine M. Saulnier! Anne L. McCartney! and Glenn R. Gibson 10 Human Milk Oligosaccharides as Prebiotics! Giovanni V. Coppa and Orazio Gabrielli 11 Inulin-Type Fructans! Jan Van Loo and Douwina Bosscher 12 Resistant Starch as a Prebiotic! Anthony R. Bird and David L. Topping 13 Effects of Prebiotic Supplementation on Bone Mineral Metabolism and Weight in Humans! Steven A. Abrams 14 Prebiotics and Lipid Metabolism! Nathalie M. Delzenne! Patrice D. Cani! and Audrey M. Neyrinck 2.4. Genomics of Lactic Acid Bacteria 15 Functional Genomics of Lactic Acid Bacteria! Tri Duong and Todd R. Klaenhammer 2.5. Proteomics of Lactic Acid Bacteria 16 Proteomic Approaches To Study Lactic Acid Bacteria! David P. A. Cohen! Elaine E. Vaughan! Willem M. de Vos! and Erwin G. Zoetendal 3. THERAPEUTIC MICROBIOLOGY IN HUMAN MEDICINE 3.1. Probiotics 17 Probiotics in Human Medicine: Overview! Jennifer K. Spinler and James Versalovic 18 Probiotics and Other Organisms in Allergy and Autoimmune Diseases! G. A. W. Rook and Nina Witt 19 Probiotics in Oral Biology and Dentistry! J. H. Meurman 20 Probiotics in Gastrointestinal Diseases! Francisco Guarner 21 Probiotics and Diseases of the Genitourinary Tract! Gregor Reid 22 Probiotics in Neurology and Psychiatry! Paul Forsythe and John Bienenstock 3.2. Prebiotics 23 Prebiotics in Human Medicine! Ian Rowland 3.3. Synbiotics 24 Synbiotics in Human Medicine! Stig Bengmark 4. THERAPEUTIC MICROBIOLOGY IN VETERINARY MEDICINE 25 Strategies for Altering the Intestinal Microbiota of Animals! Sergey R. Konstantinov and Jerry Wells 26 Probiotics in Veterinary Medicine! J. Scott Weese! Shayan Sharif! and Alex Rodiguez-Palacios 27 Prebiotics and Synbiotics in Companion Animal Science! David Hernot! Eva Ogue! George Fahey! and Robert A. Rastall 5. VIRAL STRATEGIES 28 Phage Therapy! Mikael Skurnik! Saija Kiljunen! and Maria Pajunen 6. FUTURE PROSPECTS 29 The Road Ahead: a Look at the Future! James Versalovic and Michael Wilson ...
