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Informationen zum Autor Mone Zaidi is the editor of Skeletal Biology and Medicine, Part B, published by Wiley. Klappentext This volume highlights new insights into the mechanisms of bone development, including cellular and mechanical factors, receptors, and signaling pathways and their role in both normative and pathologic states of bone.The second of two volumes, this volume comprises three sections: (1) new insights on the interaction of blood vessels and bone, particularly the role of angiogenic signals and hypoxia in osteogenesis and bone repair, as well as the dysregulation of transcription factors causing arterial calcification; (2) a new theme--integrating the evolving role of immune cells, infection, and inflammation in causing bone loss seen, for example, in various forms of arthritides; and (3) the clinical and therapeutic challenges in bone, stone, and joint diseases, and areas such as identification of high-risk patients, advent of novel therapeutic targets, genetic aberrations causing bone disease, and issues surrounding bone loss in malignancy, hyperparathyroidism, and adrenal disorders.NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas.ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member. Zusammenfassung * Part of the Annals of the New York Academy of Sciences series. *Annals volumes are available for sale as individual books or as a journal. For more information on subscriptions, please visit www. blackwellpublishing. com/nyas. . Inhaltsverzeichnis The 2nd Conference on Skeletal Medicine and Biology: Special Features: Mone Zaidi. Historical Reflections and the Future: Iain MacIntyre. Part I: Bone and Blood Vessels:. 1. Oxygen Sensing and Osteogenesis: Ying Wang, Chao Wan, Shawn R. Gilbert, and Thomas L. Clemens. 2. Perspective: The Osteoclast: An Angiogenic Cell?: Frank C. Cackowski and G. David Roodman. 3. Fetal Growth Plate: A Developmental Model of Cellular Adaptation to Hypoxia: Sylvain Provot and Ernestina Schipani. 4. Vascular Bmp-Msx2-Wnt Signaling And Oxidative Stress In Arterial Calcification: Jian-Su Shao, Ziyad Al Aly, Chung-Fang Lai, Su-Li Cheng, Jun Cai, Emily Huang, Abe Behrmann, and Dwight A. Towler. 5. Hypoxia-Mediated Mitochondrial Stress in RAW 264.7 Cells Induces Osteoclast-Like TRAP Positive Cells: Satish Srinivasan, and Narayan G. Avadhani. 6. Stem Cell Therapy in Bone Repair and Regeneration: Neeha Zaidi and Alan J. Nixon. 7. Fluid Shear Stress Up-regulates Vascular Endothelial Growth Factor Gene Expression in Osteoblasts: Mia M. Thi, Dumitru A. Iacobas, Sanda Iacobas, and David C. Spray. Part II: Skeltal Immunity and Inflamation:. 8. B Lymphocytes and the Skeleton: Mark C. Horowitz. 9. Vitamin D in Defense of the Human Immune Response: John S. Adams, Philip T. Liu, Rene Chun, Robert L. Modlin, and Martin Hewison. 10. MRI and Quantification of Draining Lymph Node Function in Inflammatory Arthritis: Steven T. Proulx, Edmund Kwok, Zhigang You, Christopher A. Beck, David J. Shealy, Christopher T. Ritchlin, Brendan F. Boyce, Lianping Xing, and Edward M. Schwarz. 11. Perfusion Abnormalities in Subchondral Bone Associated with Marrow Edema, Osteoarthritis, and Avascular Necrosis: Roy K. Aaron, Jonathan P. Dyke, Deborah McK. Ciombor, Glenn A. Tung. 12. Nuclear Factor of Activated T cell Mediates Proinflamatory Gene Expression in Response to Mechanotransduction: Ayse B. Celil Aydemir, Stephenie Lee, Dae Won Kim, Thomas R. Gardne...
