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Informationen zum Autor Gen Sobue MD, PhD Professor, Department of Neurology, Nagoya University Graduate School of Medicine Specialized field - Neurology. He graduated in 1975 from Nagoya University School of Medicine and later worked at the Nagoya University Graduate School of Medicine. Klappentext Neurodegenerative disorders and malignant tumors are usually resistant to any treatment, and the mortality rate is very high for persons with these conditions. Accordingly, finding effective treatments for these diseases is one of the most serious issues for medicine in the 21st century. In this volume, the molecular mechanisms of neurodegenerative disorders and malignant tumors are addressed, as are new therapeutic tools that exploit our understanding of these disease mechanisms. Substantial evidence for the existence of common molecular pathways for both neurodegeneration and tumor growth has been found, and many novel molecules related to both of them have also been discovered. Because integrated research on neuronal and neoplastic disorders is singularly effective in overcoming these disorders, this volume will be an excellent source of information on the state of the research in this field and on the development of its applications in human disease therapy. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas . ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order ( www.nyas.org ). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member. Zusammenfassung Neurodegenerative disorders and malignant tumors are usually resistant to any treatment! and the mortality rate is very high for persons with these conditions. Accordingly! finding effective treatments for these diseases is one of the most serious issues for medicine in the 21st century. Inhaltsverzeichnis (Please note: This is a preliminary table of contents based on the conference program.). Preface: Integrated Molecular Medicine for Neuronal and Neoplastic Disorders. Part I: Motor Neuron Diseases:. 1. Gene Expression Profiling Toward Understanding of ALS Pathogenesis: Fumiaki Tanaka, Jun-ichi Niwa, Shinsuke Ishigaki, Masahiko Yamamoto, Masahisa Katsuno, Manabu Doyu and Gen Sobue. 2. Untitled: Mimoun Azzouz. 3. Role of Polyunsaturated Fatty Acids for Misfolding Protein Aggregations; Implication for Neurodegenerative Diseases: Yeon-Jeong Kim and Ryosuke Takahashi. 4. Alleviating Neurodegeneration by an Anti-Cancer Agent - an Hsp90 Inhibitor (17-AAG): Masahiro Waza, Hiroaki Adachi, Masahisa Katsuno, Makoto Minamiyama,. Fumiaki Tanaka, and Gen Sobue. Part II: Alzheimer's Disease and Related Neurodegenerative Disorders:. 5. LRP in Amyloid-b Production and Metabolism: Guojun Bu, Judy Cam, and Celina Zerbinatti. 6. Neuronal Differentiation is Accompanied by Increased Levels of SNAP-25 Protein in Fetal Rat Primary Cortical Neurons- Implications in Neuronal Plasticity and Alzheimer's Disease: Jason A Bailey and Debomoy K. Lahiri. 7. Myosin Va Mutation in Rats is an Animal Model for the Human Hereditary Neurological Disease, Griscelli Syndrome Type 1: Yoshiko Takagishi and Yoshiharu Murata. Part III: Neuroprotective Strategy for Neurodegenerative Diseases:. 8. Brain Keratan Sulfate and Glial Scar Formation: Haoqian Zhang, Kenji Uchimura and Kenji Kadomatsu. 9. The Direct and Indirect Effects of Serofendic Acid on Neuroprotection: Yukiko Doi, Jianfeng Liang, Reiko Kuno, G...
