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Informationen zum Autor Stephan R. Targan, MDDirector, Cedars-Sinai Inflammatory Bowel and Immunobiology Research Institute, and Division of Gastroenterology, Los Angeles, CA, USAFergus Shanahan, MDProfessor and Chair, Department of Medicine and Director, Alimentary Pharmabiotic Centre, University College Cork, National University of Ireland; Professor, Department of Medicine, Cork University Hospital, Cork, IrelandLoren C. KarpResearcher/Specialist, Cedars-Sinai Inflammatory Bowel and Immunobiology Research Institute, Los Angeles, CA, USA Klappentext This is the state-of-the-art book on inflammatory bowel disease you have been waiting forWritten and edited by international experts in gastroenterology this up-to-date volume provides a complete review of the basic science behind inflammatory bowel disease (IBD), as well as evidence-based clinical guidance on diagnosis, treatment and long-term management of IBD.In 50 chapters the authors cover the latest and most promising treatment modalities and the science behind them. There are chapters which cover the advances in the medical and surgical treatment of conditions such as Crohn's disease and ulcerative colitis, as well as chapters focusing on nutrition, imaging and complementary medicine.This is an invaluable information resource for all those in the medical team treating patients with IBD. Whether you are a gastroenterologist, gastrointestinal surgeon or GI nurse specialist this book deserves a place in your library. Zusammenfassung * * Provides a detailed, comprehensive review of the basic scienceand clinical practice of inflammatory bowel disease including discussions of the controversies in this subject. * Editors all have a high profile globally in gastroenterologyand inflammatory bowel disease. Inhaltsverzeichnis List of Contributors.Preface.1. Overview of inflammatory bowel diseases: from bench to bedside and back (Fergus Shanahan, Loren C. Karp, Stephan R. Targan).2. Heterogeneity of inflammatory bowel diseases (Loren C. Karp, Stephan R. Targan).3. Epidemiology: the changing faces of Crohn's disease and ulcerative colitis (Charles Bernstein).4. Genetics of inflammatory bowel disease (Severine Vermeire, Paul Rutgeerts).5. Experimental mouse models of inflammatory bowel disease: new insights into pathogenic mechanisms (Charles O. Elson).6. The normal intestinal mucosa: a state of "controlled" inflammation (Markus Neurath, Raja Atreya).7. Innate immunity (Maria T. Abreu, Masayuki Fukata, Keith Breglio).8. Adaptive immunity (novel effector cells/TGF SMAD) (Thomas T. MacDonald, Giovanni Monteleone).9. The bacterial/epithelial/lymphocyte interface (Richard Blumberg, Robert Hershberg, Sebastian Zeissig).10. Cytokines and chemokines in mucosal homeostasis (Michel H. Maillard, Scott B. Snapper).11. Role of the microcirculation in chronic gut inflammation (Matthew B. Grisham, D. Neil Granger, Norman R. Harris, Christopher G. Kevil).12. Remission, relapse, intestinal healing and repair (Daniel K. Podolsky, Raymond J. Playford).13. Pathophysiology of inflammatory bowel disease: the bidirectional relationship of gut physiological systems and the mucosal immune system (Stephen Collins, Kenneth Croitoru).14. Pathogenesis: systemic consequences of intestinal inflammation (Konstantinos A. Papadakis, Leonidas A. Bourikas).15. Clinical course and complications of ulcerative colitis and ulcerative proctitis (Graham L. Radford-Smith, A.J. Walsh).16. Clinical features and complications of Crohn's disease (Bruce Sands).17. Practical IBD pathology in patient management (Daniel Royston, Bryan Warren).18. An endoscopist's perspective of diagnosis: when, where and what? (Simon Lo).19. Imaging in inflammatory bowel disease: CT and MR enterography, ultrasound, and enteroscop (Edward V. Loftus).20. New diagnostic approaches (integrating serologics, endoscopy and radiology and genomics) (Marla...
