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Informationen zum Autor H. Leon Bradlow is the editor of Estrogens and Human Diseases, Volume 1089, published by Wiley. Giuseppe Carruba is the editor of Estrogens and Human Diseases, Volume 1089, published by Wiley. Klappentext Estrogens may play a role, not only in classical endocrine-related tumors, such as breast or prostate, but also in several other human nosological entities, including neurodegenerative disorders, cardiovascular and immune-related diseases. This volume focuses on topics ranging from the impact of endogenous and exogenous estrogens on human development and cancer risk, to novel aspects in mechanisms of estrogen action, to estrogen implication in human malignancies (breast, prostate, liver), to the emerging role of estrogen in neurodegenerative disorders (Alzheimer's disease, multiple sclerosis, Parkinson's disease), to estrogen action in the cardiovascular system (including both genomic and nongenomic), to estrogen effects on cells of the immune system and their relevance to immune response and autoimmune diseases. The resulting inferences for clinics, diagnosis, prognosis, and treatment are also presented and extensively discussed. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member. Zusammenfassung Estrogens may play a role! not only in classical endocrine-related tumors! such as breast or prostate! but also in several other human nosological entities! including neurodegenerative disorders! cardiovascular and immune-related diseases. Inhaltsverzeichnis Preface ( H. Leon Bradlow and Giuseppe Carruba ). Inside Cancer Complexity ( Luisa M. Massimo ). In Tribute to Luigi Castagnetta -- Drawings: A Narrative Approach for Children with Cancer ( Luisa M. Massimo and Daniela A. Zarri ). Part I: Estrogens, Development and Cancer. 1. Estrogens In Prostate Development: Gail S. Prins. 2. Timing of Dietary Estrogenic Exposures and Breast Cancer Risk: Leena A. Hilakivi-Clarke. 3. From Adult Stem Cells to Cancer Stem Cells: OCT-4 Gene, Cell-Cell Communication and Hormones During Tumor Promotion: James E. Trosko. 4. Hormonal Regulation of Human Mammary Stem and Progenitor Cells: Max S. Wicha. 5. Environmental Estrogen Signaling: John A. McLachlan. Part II: New Insights into Estrogen Action:. 6. Recent Advances in Estrogen Signaling: Jan-Åke Gustaffson. 7. Lessons in Estrogen Biology from Knockout and Transgenic Animals: Kenneth S. Korach. 8. Integration of the Extra-Nuclear and Nuclear Actions of Estrogen: Ellis R. Levin. 9. Chromatin Remodelling by Estrogen and Progestin: Miguel Beato. 10. Estrogens and Epigenetic Signals: Richard G. Pestell. Part III: Estrogens and Cancer I: Breast Cancer:. 11. The Role of Endogenous Hormones in the Etiology and Prevention of Breast Cancer: The Epidemiological Evidence: Paola Muti. 12. Sustainable Lifestyle Changes for Breast Cancer Prevention: Franco Berrino. 13. The Role of Gene Silencing in Cancer Development and Progression: New Therapeutic and Prevention Targets: Frank J. Rauscher 3rd. 14. Recent Results from Clinical Trials Using SERMS to Reduce the Risk of Breast Cancer: Victor Vogel. 15. Antihormones in Prevention and Treatment of Breast Cancer: Piero Sismondi. Part IV: Estrogen and Cancer II: Prostate Cancer:. 16. Sex Steroids and Prostate Carcinogene...
