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Informationen zum Autor Girish J. Kotwal is the author of Natural Products and Molecular Therapy: First International Conference, Volume 1056, published by Wiley. Klappentext Although the peoples of all continents and cultures have been using different kinds of natural products for centuries, their mechanisms of action are poorly understood. Interestingly, most of these products "work," and paradoxically we are witnessing a great limitation of existing pharmacological targets and agents for various new diseases, such as HIV, as well as those that affect the growing aged population worldwide. This volume presents research focused on the molecular basis of action of different natural products and their applications to various diseases, including cancer, brain disorders, and infectious diseases. Promising natural therapies are scrutinized and evaluated in an effort to advance rigorous scientific analysis of these products and therapies, including achieving neuroprotection through herbal extracts, plant products, and dietary supplements. The role of antioxidants and free radicals from natural products in health and disease is also explored. The research findings presented in this volume focus on botanical, nutritional, and pharmacological strategies for improving general health and slowing normal aging, and the contributors are scientists recognized for their molecular and mechanistic work in this area. African medicine, traditional Chinese and other east Asian medicines, and ayurvedic medicine are addressed, as are a range of other natural treatments/enhancements in current use. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit www.nyas.org/membership/main.asp for more information about becoming a member. Zusammenfassung The research findings presented in this volume focus on botanical! nutritional! and pharmacological strategies for improving general health and slowing normal aging! and the contributors are scientists recognized for their molecular and mechanistic work in this area. Inhaltsverzeichnis Preface ( Girish Jayant Kotwal and Debomoy Kumar Lahiri) . Introductory Remarks: African Perspective on Natural Products and Molecular Medicine (A D Mbewu) . Part I: Allergy, Apoptosis, Inflammation, and Immunomodulators. 1. Vaccinia Virus Complement Control Protein Diminishes Formation of Atherosclerotic Lesions: Complement Is Centrally Involved in Atherosclerotic Disease (Perla Thorbjornsdottir, Ragnhildur Kolka, Eggert Gunnarsson, Slavko H. Bambir, Guðmundur Thorgeirsson, Girish J. Kotwal, and Guðmundur J. Arason). 2. Cytokine Therapy (Antony Cutler and Frank Brombacher). 3. Fighting Food Allergy: Current Approaches (Natalie E. Nieuwenhuizen and Andreas L. Lopata). 4. Parasite Mitochondria as a Target of Chemotherapy: Inhibitory Effect of Licochalcone A on the Plasmodium falciparum Respiratory Chain (Fumika Mi-Ichi, Hiroko Miyadera, Tamaki Kobayashi, Shinzaburo Takamiya, Seiji Waki, Susumu Iwata, Shoji Shibata, and Kiyoshi Kita). 5. Vaccinia Virus Complement Control Protein Ameliorates Collagen-Induced Arthritic Mice (Purushottam Jha, Scott A. Smith, David E. Justus, and Girish J. Kotwal). 6. The Vaccinia Virus N1L Protein Influences Cytokine Secretion in Vitro after Infection (Zhouning Zhang, Melissa-Rose Abrahams, Lawrence A. Hunt, Jill Suttles, William Marshall, Debomoy K. Lahiri, and Girish J. Kotwal). 7. The Vaccinia Virus N1L ORF Ma...
