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Informationen zum Autor Michael Cox is Professor and Assistant Chair of the Department of Biochemistry at the University of Wisconsin-Madison. He is currently Editor-in-chief of Critical Reviews in Biochemistry and Molecular Biology, section editor for Biochemistry in the Encyclopedia of Life Sciences and co-authors of "Lehninger's Principles of Biochemistry". George Phillips is Professor of Biochemistry and of Computer Sciences at the University of Wisconsin-Madison, section head of Biophysical Methods, Faculty of 1000 and section editor for Structural Biology in the Encyclopedia of Life Sciences . Klappentext Alle Aspekte der Biochemie von Proteinen, dazu die wichtigsten klassischen und hochmodernen Verfahren zur Aufklärung von Struktur und Funktion: Diese beiden Bände enthalten in sich geschlossene, sorgfältig begutachtete und in 11 thematische Bereiche sortierte Beiträge führender Wissenschaftler aus jeder Disziplin. Etwa ein Fünftel der Artikel behandelt Grundlagen und wendet sich eher an Anfänger. Alle anderen Arbeiten sind ausführlicher, spezieller und eher auf die Interessen von Postgraduierten und erfahrenen Forschern zugeschnitten. Die sinnvoll ausgewählten Literaturhinweise erleichtern das Einarbeiten in einzelne Themen und machen die Bände auch als schnelles Nachschlagewerk bei der Suche nach Originalarbeiten empfehlenswert. Zusammenfassung The Handbook of Proteins provides scientists and students with a focused and accessible resource covering all aspects of protein biochemistry. It describes traditional and state-of-the-art techniques for elucidating protein function and structure. . Inhaltsverzeichnis Volume 1. Contributors. Preface. How to Use This Book. Introduction. History of Protein Chemistry ( Graeme K Hunter ). Protein Structure. Amino Acid Side Chain Hydrophobicity ( Hue Sun Chan ). Amino Acid Substitutions: Effects on Protein Stability ( Zhiping Weng and Charles DeLisi ). Evolution of Protein Domains ( Corin A Yeats and Christine A Orengo ). Hydrogen Bonds in Proteins: Role and Strength ( Roderick E Hubbard ). Hydrophobic Effect ( Judith Herzfeld and Donald J Olbris ). Hydrophobic Interactions in Proteins ( Brian W Matthews ). Immunoglobulin Fold: Structures of Proteins in the Immunoglobulin Superfamily ( IsraelMGelfand, Cyrus Chothia and Alexander E Kister ). Mining Biological Databases ( Jaime Prilusky ). Molten Globule ( Anthony L Fink ). Peptide Bonds, Disulfide Bonds and Properties of Small Peptides ( Hiram F Gilbert ). Peptides: Biological Activities of Small Peptides ( Amram Mor ). Primary Protein and Nucleic Acid Three-dimensional Structure Databases ( Philip E Bourne ). Proline Residues in Proteins ( Charles M Deber and Barbara Brodsky ). Protein Databases ( Gerritsen Vivienne Baillie and Bairoch Amos ). Protein Denaturation and the Denatured State ( Per Hammarstro and Bengt-Harald Jonsson ). Protein Design ( Emmanuel Lacroix and Luis Serrano ). Protein Family Databases ( Nicola J Mulder ). Protein Motifs: ATP-binding Motifs ( Allan Matte and Louis TJ Delbaere ). Protein Motifs: GTP-binding Loop ( Guangpu Li ). Protein Motifs: the Helix-Loop-Helix Motif ( Fred Sablitzky ). Protein Motifs: the Helix-Turn-Helix Motif ( BrianW Matthews ). Protein Motifs: the Leucine Zipper ( Dmitry Krylov and Charles R Vinson ). Protein Motifs: Zinc-fingers ( David Gell, Merlin Crossley and Joel Mackay ). Protein Quaternary Structure: Subunit-Subunit Interactions ( Susan Jones and Janet M Thornton ). Protein Quaternary Structure: Symmetry Patterns ( Ronald E Stenkamp ). Pro...
List of contents
Volume 1. Contributors. Preface. How to Use This Book. Introduction. History of Protein Chemistry ( Graeme K Hunter ). Protein Structure. Amino Acid Side Chain Hydrophobicity ( Hue Sun Chan ). Amino Acid Substitutions: Effects on Protein Stability ( Zhiping Weng and Charles DeLisi ). Evolution of Protein Domains ( Corin A Yeats and Christine A Orengo ). Hydrogen Bonds in Proteins: Role and Strength ( Roderick E Hubbard ). Hydrophobic Effect ( Judith Herzfeld and Donald J Olbris ). Hydrophobic Interactions in Proteins ( Brian W Matthews ). Immunoglobulin Fold: Structures of Proteins in the Immunoglobulin Superfamily ( IsraelMGelfand, Cyrus Chothia and Alexander E Kister ). Mining Biological Databases ( Jaime Prilusky ). Molten Globule ( Anthony L Fink ). Peptide Bonds, Disulfide Bonds and Properties of Small Peptides ( Hiram F Gilbert ). Peptides: Biological Activities of Small Peptides ( Amram Mor ). Primary Protein and Nucleic Acid Three dimensional Structure Databases ( Philip E Bourne ). Proline Residues in Proteins ( Charles M Deber and Barbara Brodsky ). Protein Databases ( Gerritsen Vivienne Baillie and Bairoch Amos ). Protein Denaturation and the Denatured State ( Per Hammarstro and Bengt Harald Jonsson ). Protein Design ( Emmanuel Lacroix and Luis Serrano ). Protein Family Databases ( Nicola J Mulder ). Protein Motifs: ATP binding Motifs ( Allan Matte and Louis TJ Delbaere ). Protein Motifs: GTP binding Loop ( Guangpu Li ). Protein Motifs: the Helix Loop Helix Motif ( Fred Sablitzky ). Protein Motifs: the Helix Turn Helix Motif ( BrianW Matthews ). Protein Motifs: the Leucine Zipper ( Dmitry Krylov and Charles R Vinson ). Protein Motifs: Zinc fingers ( David Gell, Merlin Crossley and Joel Mackay ). Protein Quaternary Structure: Subunit Subunit Interactions ( Susan Jones and Janet M Thornton ). Protein Quaternary Structure: Symmetry Patterns ( Ronald E Stenkamp ). Protein Secondary Structures: Prediction ( John Marc Chandonia ). Protein Sequence Databases ( Winona C Barker ). Protein Stability ( C Nick Pace and Gerald R Grimsley ). Protein Structural Flexibility: Molecular Motions ( Richard H Henchman and J Andrew McCammon ). Protein Structure Classification ( Frances MG Pearl, Christine A Orengo and Janet M Thornton ). Protein Structure: Unusual Covalent Bonds ( Nancy L Scott and Juliette T J Lecomte ). Protein Tertiary Structures: Prediction from Amino Acid Sequences ( Hongyu Zhang ). Protein Unfolding and Denaturants ( Lars Konermann ). Protein: Cotranslational and Posttranslational Modification in Organelles ( Doug A Brooks ). Proteins: Fundamental Chemical Properties ( Alain J Cozzone ). Structural Databases of Biological Macromolecules ( Helen M Berman ). Unstructured Proteins ( A Keith Dunker ). Protein Synthesis. Chaperones, Chaperonin and Heat Shock Proteins ( Valerio Consalvi and Roberta Chiaraluce ). Chaperonins ( Valerio Consalvi and Roberta Chiaraluce ). Codon Usage in Molecular Evolution ( Richard L Grantham ). Protein Folding In Vivo ( Sarah Teter and F Ulrich Hartl ). Protein Synthesis Inhibitors ( D N Wilson, U Stelzl and Knud H Nierhaus ). Protein Synthesis Initiation in Bacteria ( Marianne Grunberg Manago ). Proteins: Postsynthetic Modification Function and Physical Analysis ( Brigitte Wittmann Liebold and Theodora Choli Papadopoulou ). Protein Degradation. Amino Acid Degradation ( Gary Sawers ). Lysosomal Degradation of Proteins ( J Fred Dice ). Protease Complexes ( Marion Schmidt and Daniel Finley ). Proteases ( Alan J Barrett and Neil D Rawlings ). Ubiquitin Pathway ( Y Amy Lam and Cecile M Pickart ). Enzymes. Binding Constants: Measurement and Biological Range ( Donald J Winzor ). Engineered Enzymes ( Ben M Dunn ). Enzymatic Rate Enhancements ( Daniel M Quinn and R Steven Sikorski ). Enzyme Activity: Control ( Shorena Nadaraia, George J Yohrling IV, George C T Jiang, John M Flanagan and Kent E Vrana ). Enzyme Classification and Nomenclature ( Sinead Boyce and Keith F Tipton )....
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"Zusammenfassend handelt es sich bei dem Handbook of Proteins um einen hervorragenden, auf dem Stand der Wissenschaft und von den Experten des Feldes geschriebenen Überblick über eines der spannendsten Themen in der Biologie - die Proeteine."
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